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半封闭循环式真空辅助微创经皮肾镜取石术在儿科人群中的应用:两家三级转诊中心的初步经验。

Semi-closed-circuit vacuum-assisted mini percutaneous nephrolithotomy in the pediatric population: the initial experience of two tertiary referral centers.

机构信息

Unit of Urology, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy -

Unit of Pediatric Urology, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

出版信息

Minerva Urol Nephrol. 2022 Feb;74(1):93-101. doi: 10.23736/S2724-6051.20.03951-X. Epub 2020 Oct 5.

Abstract

BACKGROUND

Percutaneous nephrolithotomy (PCNL) is the gold-standard for complex renal stones treatment in the pediatric population. While the miniaturization of PCNL reduces the risk of bleeding, it can hinder surgical and functional outcomes. The aim of the study was to assess the safety and feasibility of semi-closed-circuit vacuum-assisted Mini-PCNL (vmPCNL) in pediatric patients.

METHODS

From January 2017 to December 2018, we prospectively collected data on consecutive vmPCNLs from two European tertiary referral centers. The procedure was performed with the ClearPetra (Well Lead Medical Co., Ltd., Guangzhou, China) access sheath equipped with a lateral arm connected to the aspiration system (pressure setting ~120-150 cmH2O) by a 200 Ml plastic stone collector. Pre-, intra- and postoperative data and costs were analyzed. The stone-free rate (SFR) was defined as absence of residual fragments >4 mm with either ultrasound or kidney, ureter, and bladder X-ray.

RESULTS

Eighteen vmPCNLs were performed in 16 renal units of 13 children. The median age was 119 months (IQR: 97-160) and the weight was 29 Kg (IQR: 25-40). The median cumulative stone size was 32 mm (22-46) with 8 (44.4%) cases of staghorn stones. The OT was 128 min (IQR: 99-167). The basketing was unnecessary in 6/18 (33%) cases. Neither intra-operative complications nor blood transfusions occurred. Postoperative fever was observed in 5/18 (27.8%) cases; in one case a double J ureteral stent was placed for concomitant hydronephrosis. The SFR was 81.3% (13/16), rising to 93.8% (15/16) after ancillary procedures. The materials costs of a vmPCNL (734.8 €) were comparable to mini-PCNL using a reusable set (710.7 €).

CONCLUSIONS

The vmPCNL seems to be sustainable, safe and feasible for kidney stones treatment in the pediatric population.

摘要

背景

经皮肾镜碎石术(PCNL)是儿童复杂肾结石治疗的金标准。虽然 PCNL 的微创化降低了出血风险,但可能会影响手术和功能结果。本研究旨在评估半闭路真空辅助 Mini-PCNL(vmPCNL)在儿科患者中的安全性和可行性。

方法

2017 年 1 月至 2018 年 12 月,我们前瞻性地收集了来自欧洲两个三级转诊中心的连续 vmPCNL 数据。该手术使用 ClearPetra(广州威联德医疗科技有限公司)入路鞘,配备带有侧臂的吸引系统(压力设置为~120-150cmH2O),通过 200ml 塑料结石收集器连接。分析术前、术中及术后数据和成本。无结石率(SFR)定义为超声或肾脏、输尿管和膀胱 X 射线检查无残留碎片>4mm。

结果

13 名儿童的 16 个肾脏单位共进行了 18 例 vmPCNL。中位年龄为 119 个月(IQR:97-160),体重为 29kg(IQR:25-40)。中位累积结石大小为 32mm(22-46),其中 8 例(44.4%)为鹿角形结石。手术时间为 128 分钟(IQR:99-167)。6/18(33%)例无需篮式取石。无术中并发症和输血。18 例中有 5 例(27.8%)术后发热;其中 1 例因并发肾积水放置双 J 输尿管支架。16 个肾脏单位中 13 个(81.3%)达到 SFR,辅助治疗后 15 个(93.8%)达到 SFR。vmPCNL 的材料成本(734.8 欧元)与使用可重复套件的 mini-PCNL(710.7 欧元)相当。

结论

vmPCNL 似乎可持续、安全且适用于儿童肾结石的治疗。

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