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经皮切开引流术与切开引流术治疗皮肤及软组织脓肿的比较:系统评价和荟萃分析。

Comparison of the Loop Technique With Incision and Drainage for Skin and Soft Tissue Abscesses: A Systematic Review and Meta-analysis.

机构信息

From the, Department of Emergency Medicine, Rush University Medical Center, Chicago, IL, USA.

and the, Department of Military and Emergency Medicine, Uniformed Services University, Bethesda, MD, USA.

出版信息

Acad Emerg Med. 2021 Mar;28(3):346-354. doi: 10.1111/acem.14151. Epub 2020 Nov 9.

Abstract

BACKGROUND

Cutaneous abscesses are common presentations to the emergency department. While the primary treatment for most abscesses is conventional incision and drainage (CID), this is painful and can lead to multiple return visits. The loop drainage technique (LDT) has been proposed as an alternate, less-invasive approach to abscess management. The primary outcome of this study was to compare LDT with CID for skin and soft tissue abscesses.

METHODS

PubMed, Scopus, CINAHL, LILACS, Google Scholar, the Cochrane Database of Systematic Reviews, the Cochrane Central Register of Controlled Trials, and bibliographies of selected articles were assessed for all retrospective, prospective observational, and randomized controlled trials comparing treatment failures between LDT and CID among patients with skin and soft tissue abscesses. Data were dual extracted into a predefined worksheet and quality analysis was performed using the Cochrane Risk of Bias tool or the Newcastle-Ottawa scale. Data were summarized and presented as odds ratios (ORs) with 95% confidence intervals (CIs). Subgroup analyses were performed for adult and pediatric patients.

RESULTS

A total of 1,374 studies were identified with eight studies (n = 910 patients) selected for inclusion. Overall, CID failed in 69 of 487 patients (14.17%), while LDT failed in 35 of 423 patients (8.27%). There was an OR of 2.02 (95% CI = 1.29 to 3.18) in favor of higher failures in the CID group. This finding remained consistent with only randomized controlled trials (OR = 1.75, 95% CI = 1.07 to 2.86), but no difference was identified in the adult or pediatric subgroups.

CONCLUSION

The LDT was associated with reduced treatment failures when compared with CID. Future studies should further assess the impact on pain, cosmetic outcomes, and health care costs.

摘要

背景

皮肤脓肿是急诊科常见的就诊原因。虽然大多数脓肿的主要治疗方法是传统的切开引流(CID),但这种方法很痛苦,而且可能导致多次复诊。环式引流技术(LDT)已被提议作为一种替代的、侵入性较小的脓肿管理方法。本研究的主要结局是比较 LDT 与 CID 治疗皮肤和软组织脓肿的效果。

方法

检索了 PubMed、Scopus、CINAHL、LILACS、Google Scholar、Cochrane 系统评价数据库、Cochrane 对照试验中心注册库和选定文章的参考文献,以获取所有比较 LDT 与 CID 治疗皮肤和软组织脓肿患者治疗失败的回顾性、前瞻性观察性和随机对照试验。数据被双重提取到预定义的工作表中,并使用 Cochrane 偏倚风险工具或 Newcastle-Ottawa 量表进行质量分析。数据以比值比(OR)和 95%置信区间(CI)进行汇总和呈现。对成人和儿科患者进行了亚组分析。

结果

共检索到 1374 篇研究,最终纳入 8 项研究(n=910 例患者)。总体而言,CID 在 487 例患者中失败 69 例(14.17%),而 LDT 在 423 例患者中失败 35 例(8.27%)。CID 组失败率更高的 OR 为 2.02(95% CI=1.29 至 3.18)。这一发现与仅包括的随机对照试验一致(OR=1.75,95% CI=1.07 至 2.86),但在成人或儿科亚组中未发现差异。

结论

与 CID 相比,LDT 与治疗失败率降低相关。未来的研究应进一步评估其对疼痛、美容结局和医疗保健成本的影响。

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