前列腺特异性膜抗原正电子发射断层扫描引导放疗。
Prostate-specific Membrane Antigen Positron Emission Tomography-guided Radiotherapy.
机构信息
Department of Radiation Oncology, University of California Los Angeles, Los Angeles, CA, USA; Department of Urology, University of California Los Angeles, Los Angeles, CA, USA.
Department of Radiation Oncology, University of California Los Angeles, Los Angeles, CA, USA; Department of Urology, University of California Los Angeles, Los Angeles, CA, USA; Department of Radiation Oncology, Veteran Affairs Greater Los Angeles Healthcare System, Los Angeles, CA, USA.
出版信息
Eur Urol Focus. 2021 Mar;7(2):250-253. doi: 10.1016/j.euf.2020.09.020. Epub 2020 Oct 10.
Radiotherapy has curative potential for patients with newly diagnosed localized prostate cancer and biochemical recurrence after radical prostatectomy, and can offer durable treatment responses for patients with oligometastatic disease. The success of radiotherapy in these settings relies on an accurate understanding of the extent of disease that is present and the precise anatomic localization of sites of disease. In this mini review, we provide an overview of recent data evaluating the role of positron emission tomography for assessing prostate-specific membrane antigen distribution in guiding radiotherapy in these settings. PATIENT SUMMARY: This mini review examines current evidence for the use of prostate-specific membrane antigen positron emission tomography/computed tomography to guide radiotherapy for patients with newly diagnosed localized prostate cancer, those with recurrences after radical prostatectomy, and those with oligometastatic disease.
放射治疗对新诊断的局限性前列腺癌和根治性前列腺切除术后生化复发的患者具有治愈潜力，并可为寡转移疾病患者提供持久的治疗反应。在这些情况下，放射治疗的成功依赖于对存在的疾病程度的准确理解和疾病部位的精确解剖定位。在这个迷你综述中，我们提供了最近评估正电子发射断层扫描在指导这些情况下放射治疗中前列腺特异性膜抗原分布的作用的数据概述。
患者总结
本迷你综述检查了使用前列腺特异性膜抗原正电子发射断层扫描/计算机断层扫描来指导新诊断的局限性前列腺癌、根治性前列腺切除术后复发和寡转移疾病患者放射治疗的现有证据。
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