Cunto Eleonora R, Colque Ángel M, Herrera María Paula, Chediack Viviana, Staneloni María Inés, Saúl Pablo A
Hospital de Infecciosas Francisco J. Muñiz, Buenos Aires, Argentina. E-mail:
Complejo Médico Churruca Visca, Buenos Aires, Argentina.
Medicina (B Aires). 2020;80(5):531-540.
Severe skin and soft tissue infections present a high morbidity and mortality and require a complex surgical treatment. Its estimated annual incidence is 0.3 to 5 cases per 10 000 people. The most common etiologic agents are Streptococcus pyogenes, Staphylococcus aureus, anaerobes and gram-negative bacilli. A prompt diagnosis and the timely initiation of an empirical antibiotic scheme and repeated surgical debridement can avert a worrisome outcome. New therapeutic options are promising, especially for infections caused by multidrug resistant germs. A multidisciplinary approach is fundamental for the correct management of these conditions.
严重皮肤和软组织感染具有较高的发病率和死亡率，需要复杂的外科治疗。其估计年发病率为每万人0.3至5例。最常见的病原体是化脓性链球菌、金黄色葡萄球菌、厌氧菌和革兰氏阴性杆菌。及时诊断并及时启动经验性抗生素方案和反复进行外科清创术可避免不良后果。新的治疗选择前景广阔，尤其是对于由多重耐药菌引起的感染。多学科方法对于正确处理这些病症至关重要。
