Division of Vascular and Endovascular Surgery, Boston Medical Center, Boston University School of Medicine, Boston, Mass.
Division of Vascular and Endovascular Surgery, Boston Medical Center, Boston University School of Medicine, Boston, Mass.
J Vasc Surg. 2021 May;73(5):1771-1777. doi: 10.1016/j.jvs.2020.09.020. Epub 2020 Oct 15.
Arteriovenous (AV) access is the preferred hemodialysis modality to avoid the complications associated with tunneled dialysis catheters (TDCs). Despite efforts to create timely AV access, many patients still initiate hemodialysis through TDCs. Our goal was to determine the patient factors associated with having a TDC present at initial AV access creation and how this affects survival.
We performed a single-center, retrospective review of all patients who had undergone initial AV fistula creation from 2014 to 2019. Patients with previous peritoneal or AV access were excluded. Univariable and multivariable analyses were used to identify associations with a TDC present at initial AV access creation and patient survival.
Of 509 patients who had undergone initial AV access creation, a TDC was present in 280 (55%). The mean patient age was 59.7 ± 14.1 years. The access types were brachiocephalic (47.2%), brachiobasilic (22.4%), radiocephalic (15.5%), and prosthetic (12.6%). The patients with a TDC compared with those without a TDC were less likely to be obese (68.9% vs 54.2%), more likely to be homeless (10.4% vs 4.8%), and more likely to be an inpatient (44.6% vs 18.8%). They were less likely to have seen a primary care physician within 1 year preoperatively (54.3% vs 88.6%) and a nephrologist within 3 months preoperatively (39.3% vs 93%; P < .05 for all). On multivariable analysis, the presence of a TDC at initial AV access creation was associated with no nephrology visit within 3 months preoperatively (odds ratio [OR], 25; 95% confidence interval [CI], 12.5-50; P < .001), homeless status (OR, 2.6; 95% CI, 1.1-6.2; P = .03), and the absence of obesity (OR, 1.8; 95% CI, 1.1-2.9; P = .02). The 1-year survival was similar for patients with (95%) and without (94.8%) a TDC (P = .36) as confirmed by multivariable analysis (hazard ratio, 1.2; 95% CI, 0.65-2.1; P = .63).
The absence of a preoperative nephrology visit, homeless status, and the absence of obesity were associated with a TDC present at initial AV access creation. However, the presence of a TDC did not appear to confer changes in short-term survival. Targeted improvements in high-risk populations such as increasing the frequency of preoperative subspecialty evaluation might be warranted to reduce TDC placement before AV access creation at urban safety-net hospitals.
动静脉(AV)通路是首选的血液透析方式,可避免与隧道透析导管(TDC)相关的并发症。尽管努力创建及时的 AV 通路,但许多患者仍通过 TDC 开始血液透析。我们的目标是确定与初始 AV 通路创建时存在 TDC 相关的患者因素,以及这如何影响生存。
我们对 2014 年至 2019 年间所有接受初始 AV 瘘管创建的患者进行了单中心回顾性研究。排除了既往有腹膜或 AV 通路的患者。采用单变量和多变量分析来确定与初始 AV 通路创建时存在 TDC 相关的因素以及患者的生存情况。
在接受初始 AV 通路创建的 509 例患者中,有 280 例(55%)存在 TDC。患者的平均年龄为 59.7±14.1 岁。通路类型为头臂静脉(47.2%)、肱动脉-肱静脉(22.4%)、桡动脉-头静脉(15.5%)和假体(12.6%)。与无 TDC 的患者相比,有 TDC 的患者不太可能肥胖(68.9% vs 54.2%),更有可能无家可归(10.4% vs 4.8%),更有可能为住院患者(44.6% vs 18.8%)。他们不太可能在术前 1 年内看过初级保健医生(54.3% vs 88.6%),在术前 3 个月内看过肾病医生(39.3% vs 93%;所有 P 值均<.05)。多变量分析显示,初始 AV 通路创建时存在 TDC 与术前 3 个月内无肾病就诊(优势比 [OR],25;95%置信区间 [CI],12.5-50;P<.001)、无家可归状态(OR,2.6;95%CI,1.1-6.2;P=.03)和无肥胖症(OR,1.8;95%CI,1.1-2.9;P=.02)有关。有 TDC(95%)和无 TDC(94.8%)患者的 1 年生存率相似(P=.36),这在多变量分析中得到了证实(风险比,1.2;95%CI,0.65-2.1;P=.63)。
术前无肾病就诊、无家可归状态和无肥胖症与初始 AV 通路创建时存在 TDC 有关。然而,TDC 的存在似乎并没有改变短期生存率。在城市安全网医院,针对高危人群(如增加术前专科评估的频率)进行有针对性的改进,可能有助于减少 AV 通路创建前 TDC 的放置。