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经动脉栓塞术治疗难治性出血

Transarterial Embolization in the Management of Intractable Haemorrhage.

机构信息

Department of Urology, Central Hospital of Bolzano, Bolzano, Italy,

College of Health-Care Professions, Claudiana, Bolzano, Italy,

出版信息

Urol Int. 2021;105(1-2):95-99. doi: 10.1159/000511123. Epub 2020 Oct 16.

Abstract

INTRODUCTION

The purpose of this study was to evaluate the effectiveness and long-term results of selective transarterial iliac embolization (STIE) in patients with intractable bladder haemorrhage (IBH).

METHODS

Twenty-five patients with a median age of 84 (range 65-94) years underwent STIE because of IBH between 2002 and 2020. The median follow-up time was 3 (mean 13.9) months. Patients were treated because of bleeding bladder or prostate cancer, radiation-induced haemorrhagic cystitis, and other conditions. Success was defined as technical success (feasibility to embolize bilateral hypogastric arteries or neoplastic arteries) and as clinical success (absence of further or additional therapy).

RESULTS

Twenty-five patients with a median age of 84 years with a median hospital stay of 7 days were embolized at our institution. In total, 60% required additional therapy. Only 20% had minor complications, but no complication major was seen; 60% needed an additional therapy because of continuous bleeding. Our 30-day, 90-day, 6-month, and 12-month mortality rates were 28, 44, 64, and 76%, respectively.

CONCLUSIONS

STIE in IBH is a safe, well-tolerated, and feasible procedure for palliating haematuria patients in poor general condition. Major complications are very rarely seen. However, patients often need additional therapy after STIE.

摘要

介绍

本研究旨在评估选择性髂内动脉栓塞(STIE)治疗难治性膀胱出血(IBH)的有效性和长期结果。

方法

2002 年至 2020 年间,25 例年龄中位数为 84 岁(范围 65-94 岁)的患者因 IBH 接受了 STIE。中位随访时间为 3(平均 13.9)个月。患者因膀胱或前列腺癌出血、放射性出血性膀胱炎和其他疾病接受治疗。成功定义为技术成功(双侧下腹动脉或肿瘤性动脉栓塞的可行性)和临床成功(无进一步或额外治疗)。

结果

25 例年龄中位数为 84 岁、中位住院时间为 7 天的患者在我们机构接受了栓塞治疗。总共 60%的患者需要额外的治疗。只有 20%的患者出现轻微并发症,但没有出现严重并发症;60%的患者因持续出血需要额外的治疗。我们的 30 天、90 天、6 个月和 12 个月的死亡率分别为 28%、44%、64%和 76%。

结论

STIE 治疗 IBH 是一种安全、耐受良好且可行的方法,可缓解一般状况较差的血尿患者的病情。严重并发症很少见。然而,患者在 STIE 后通常需要额外的治疗。

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