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B族链球菌疾病与定植的发病率——一项临床流行病学研究

[Incidence of B streptococcal diseases and colonization--a clinico-epidemiological study].

作者信息

Halle E, Halle H, Günther E, Grauel E L, Schmidt G

出版信息

Zentralbl Gynakol. 1987;109(13):830-6.

PMID:3307227
Abstract

The incidence of newborn infections caused by group B streptococci (GBS) has risen significantly in recent years. In 1983 and 1984 ten GBS diseases of the newborns were registered in the Department of Neonatology of the University Hospital (Charité). This is a morbidity of 1.2 per 1,000 live births. Eight infants showed an early onset and 2 a late onset type. Three of the neonates died. These were term infants with a birth weight of more than 2,500 g. The isolated types in these cases were Ia, Ia/c and III. In 1983 and 1984 430 nonselected women between the 34th and 40th weeks of gestation were examined for GBS colonization. One rectal, vaginal and cervical swab was collected from each women and cultured both in a selective broth medium and a selective blood agar plate. The colonization rate was 11.4% in pregnant women. The most frequent colonized region was the rectum, followed by vagina and cervix. Cultures from infants were obtained from throat, left and right ear. 2.7% of the newborns were positive for GBS. The most frequent isolated types are III/R and Ia. In all cases, positive for maternal and neonatal colonization, the isolated types were identical.

摘要

近年来,由B族链球菌(GBS)引起的新生儿感染发病率显著上升。1983年和1984年,大学医院(夏里特医院)新生儿科登记了10例新生儿GBS疾病。这相当于每1000例活产中有1.2例发病。8例婴儿表现为早发型,2例为晚发型。3例新生儿死亡。这些均为足月儿,出生体重超过2500克。这些病例中分离出的菌株类型为Ia、Ia/c和III型。1983年和1984年,对430名妊娠34至40周的未经过筛选的妇女进行了GBS定植检查。从每位妇女身上采集一份直肠、阴道和宫颈拭子,分别在选择性肉汤培养基和选择性血琼脂平板上进行培养。孕妇的定植率为11.4%。最常被定植的部位是直肠,其次是阴道和宫颈。从婴儿的咽喉、左耳和右耳采集培养样本。2.7%的新生儿GBS检测呈阳性。最常分离出的菌株类型是III/R和Ia型。在所有母亲和新生儿定植均呈阳性的病例中,分离出的菌株类型相同。

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