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妊娠与先天性心脏病:风险评估与管理简述。

Pregnancy and Congenital Heart Disease: A Brief Review of Risk Assessment and Management.

机构信息

Mount Sinai Adult Congenital Heart Disease Center, Mount Sinai Cardiovascular Institute.

Division of Maternal Fetal Medicine, Department of Obstetrics & Gynecology and Women's Health, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, New York.

出版信息

Clin Obstet Gynecol. 2020 Dec;63(4):836-851. doi: 10.1097/GRF.0000000000000579.

Abstract

Cardiac disease is a leading cause of morbidity and mortality in pregnant women. An increased prevalence of the cardiovascular disease has been found in women of childbearing age, in which the responsibility of the treating physician extends to the mother and to the unborn fetus. As a result, care of these high-risk pregnant women with cardiovascular disease including those with congenital heart disease (CHD) require a team approach including specialists in maternal-fetal medicine, adult congenital cardiology, and obstetrical anesthesia. The human body undergoes significant amounts of physiological changes during this period of time and the underlying cardiac disease can affect both the mother and the fetus. Today, most female children born with CHD will reach childbearing age. For many women with complex CHD, carrying a pregnancy has a moderate to high risk for both the mother and her fetus. This chapter will review the epidemiology, risk factors, clinical presentation including common signs and symptoms, physiological changes in pregnancy, and the medical approach including cardiac medications, percutaneous interventions, and surgical procedures for pregnant women with CHD.

摘要

心脏病是导致孕妇发病率和死亡率的主要原因。在育龄妇女中发现心血管疾病的患病率增加,其中治疗医生的责任不仅限于母亲,还包括未出生的胎儿。因此,包括患有先天性心脏病 (CHD) 在内的患有心血管疾病的高危孕妇需要团队治疗,团队成员包括母胎医学、成人先天性心脏病学和产科麻醉学专家。在此期间,人体会发生大量的生理变化,潜在的心脏病会影响母亲和胎儿。如今,大多数患有 CHD 的女性患儿都将达到生育年龄。对于许多患有复杂 CHD 的女性来说,怀孕对母亲和她的胎儿都存在中等到高风险。本章将回顾 CHD 孕妇的流行病学、风险因素、临床表现(包括常见体征和症状)、妊娠期间的生理变化以及心脏药物、经皮介入和手术治疗方法。

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