Department of Cardiovascular Surgery, Henan Provincial People's Hospital, Fuwai Central Cardiovascular Hospital, People's Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Department of Cardiovascular Surgery, Henan Provincial People's Hospital, Fuwai Central Cardiovascular Hospital, People's Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Ann Thorac Surg. 2021 Nov;112(5):1532-1536. doi: 10.1016/j.athoracsur.2020.07.079. Epub 2020 Oct 17.
Surgical transpleural minimally invasive occlusion of perimembranous and muscular ventral septal defects provides excellent results, but there is limited experience in outlet ventral septal defects (OVSDs) because of the specific anatomy and because OVSDs may occur with aortic valve prolapse.
The procedure was performed in 84 children (mean age, 2.5 ± 2.3 years; mean weight, 12.1 ± 10.3 kg) between July 2014 and December 2018 at the Children's Heart Center of Henan Provincial People's Hospital. An approximately 2-cm right subaxillary incision was made, and the right ventricle was punctured under transesophageal echocardiographic guidance. The OVSD was occluded under transesophageal echocardiographic guidance with an asymmetric occluder.
Mean size of the OVSDs and the occluders was 4.6 ± 1.0 and 6.2 ± 1.2 mm, respectively. No patients died and no complications occurred, such as third-degree atrioventricular block, new aortic regurgitation, reoperation, or serious infection. All patients were observed for 32.1 ± 17.1 months. After surgery, there were 4 cases of residual shunt, which resolved spontaneously during follow-up. No complications, such as reoperation, aortic regurgitation, atrioventricular block, or occluder detachment, were observed during the follow-up period.
Occluding OVSDs using an asymmetric occluder through the subaxillary approach was safe and effective, with satisfactory short-term and mid-term results. Further follow-up is required regarding the long-term results.
经胸微创膜周部和肌部室间隔缺损封堵术效果极佳,但由于出口型室间隔缺损(outlet ventricular septal defect,OVSD)的特殊解剖结构,以及其可能与主动脉瓣脱垂同时发生,因此经验有限。
2014 年 7 月至 2018 年 12 月,在河南省人民医院儿童心脏中心,对 84 例(平均年龄 2.5±2.3 岁,平均体重 12.1±10.3kg)儿童进行了该手术。取右腋下约 2cm 的切口,在经食管超声心动图引导下穿刺右心室。经食管超声心动图引导下,使用非对称封堵器对 OVSD 进行封堵。
OVSD 和封堵器的平均直径分别为 4.6±1.0mm 和 6.2±1.2mm。无患者死亡,也无三度房室传导阻滞、新发主动脉瓣反流、再次手术或严重感染等并发症发生。所有患者均随访 32.1±17.1 个月。术后有 4 例残余分流,随访期间自行缓解。随访期间无再手术、主动脉瓣反流、房室传导阻滞或封堵器脱落等并发症发生。
经腋下入路使用非对称封堵器封堵 OVSD 安全有效,短期和中期效果满意。需要进一步随访以了解长期结果。