Pezzoli Matteo, Zeppieri Marco, Patel Bhupendra C.
Ospedale San Giovanni Bosco Torino
University Hospital of Udine, Italy
Dacryostenosis is an acquired or congenital condition resulting from nasolacrimal duct obstruction (NLDO), which causes epiphora or watery eyes. The term "dacryostenosis" is derived from the Greek words ("tear") and ("narrowing"), which refers to the congenital or acquired narrowing of the nasolacrimal duct. The ocular surface remains consistently moistened by tears produced by specialized lacrimal glands. After nourishing the ocular surface, these tears flow into the nose through the nasolacrimal duct. The secretory lacrimal system relies on the integral function of the lacrimal glands. When addressing dacryostenosis, it is essential to grasp the mechanisms of tear production and the anatomy of the tear drainage system (see The Lacrimal Drainage Pathway). The 4 key anatomical components that constitute the excretory system are listed below. 1. These are orifices situated on the surface of eyelids. 2. These are small channels connecting the puncta with the nasolacrimal sac. 3. This serves as a reservoir for tears that overflow. . 4. This carries tears from the eyes into the nasal cavity. Epiphora is a condition that results from anomalies affecting any part of the excretory system and causing excessively watery eyes and an overflow of tears. The congenital form of dacryostenosis is the most prevalent cause of persistent tearing and ocular discharge, affecting nearly 6% of all infants. This condition results from abnormal canalization of the nasolacrimal duct, in utero, at the end closest to the nose. In contrast, the acquired form of dacryostenosis can be classified as either primary or secondary, depending on the underlying cause. The causes of primary acquired NLDO (PANDO) include inflammation, fibrosis, mucosal edema, vascular congestion, stasis, infections, or trauma to the lacrimal apparatus, which can result in partial or total obstruction of the duct later in life. Menstrual hormonal changes, osteoporosis, and the gradual narrowing of the lacrimal duct, particularly in females older than 40, contribute to increased susceptibility. Other potential underlying factors include infections, inflammation, neoplasms, and mechanical obstruction. The presence of a mucoid discharge and persistent tearing are the 2 classic clinical symptoms of dacryostenosis. These symptoms typically appear in newborns during the first few weeks to months of life. Although dacryostenosis is generally benign, untreated cases can advance to recurrent conjunctivitis and dacryocystitis, potentially causing various complications such as stained tears, frequent eye infections, preseptal or orbital cellulitis, sepsis, meningitis, or brain abscess in both children and adults. Therefore, it is crucial to address dacryostenosis promptly to prevent the onset of severe medical problems.
泪道狭窄是一种由鼻泪管阻塞(NLDO)导致的后天性或先天性病症,可引起溢泪或流泪。术语“泪道狭窄”源自希腊语“δάκρυον”(意为“眼泪”)和“στενός”(意为“变窄”),指鼻泪管先天性或后天性变窄。眼表持续由特殊泪腺产生的泪水保持湿润。滋养眼表后,这些泪水通过鼻泪管流入鼻腔。分泌性泪液系统依赖于泪腺的整体功能。在处理泪道狭窄问题时,必须掌握泪液产生机制和泪液引流系统的解剖结构(见“泪液引流途径”)。构成排泄系统的4个关键解剖组成部分如下。1. 这些是位于眼睑表面的小孔。2. 这些是连接小孔与鼻泪囊的小通道。3. 这是溢出泪水的储存处。4. 这将泪水从眼睛输送到鼻腔。溢泪是一种因排泄系统任何部位异常而导致泪水过多和流泪的病症。先天性泪道狭窄是持续性流泪和眼部分泌物的最常见原因,影响近6%的所有婴儿。这种情况是由于鼻泪管在子宫内靠近鼻子一端的管道化异常所致。相比之下,后天性泪道狭窄可根据潜在病因分为原发性或继发性。原发性后天性鼻泪管阻塞(PANDO)的病因包括炎症、纤维化、黏膜水肿、血管充血、淤滞、感染或泪器创伤,这些可在以后生活中导致泪管部分或完全阻塞。月经激素变化、骨质疏松以及泪管逐渐变窄,尤其是40岁以上女性,会增加易感性。其他潜在的潜在因素包括感染、炎症、肿瘤和机械性阻塞。黏液样分泌物和持续性流泪是泪道狭窄的2个典型临床症状。这些症状通常在新生儿出生后的头几周至几个月出现。虽然泪道狭窄通常是良性的,但未经治疗的病例可能发展为复发性结膜炎和泪囊炎,可能导致各种并发症,如泪痕、频繁眼部感染、睑前或眼眶蜂窝织炎、败血症、脑膜炎或儿童和成人的脑脓肿。因此,及时处理泪道狭窄以预防严重医疗问题的发生至关重要。