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独居与痴呆症药物使用者的药物相关使用情况。

Living alone for people on dementia medication: related use of drugs.

机构信息

Centre for Public Health, Queen's University Belfast, Belfast, United Kingdom.

Centre for Public Health, Queen’s University Belfast, Belfast, United Kingdom.

出版信息

Aging (Albany NY). 2020 Oct 21;12(20):20924-20929. doi: 10.18632/aging.104125.

DOI:10.18632/aging.104125
PMID:33085648
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7655219/
Abstract

Approximately one-third of people with dementia in the United Kingdom live alone. People living alone with dementia may receive different treatment for dementia and may have different comorbidities compared to people who live with a caregiver. This study explored differences in medication and demographic characteristics between people living alone with dementia and those living with a caregiver in Northern Ireland. People with dementia were identified through the first date that a dementia management medication was prescribed between 2010 and 2016. In total, 25,418 people were prescribed a dementia management medication. Data for whether people with dementia lived alone was extracted through the National Health Application and Infrastructure Services and from national datasets through the Honest Broker Service. Approximately 35% (n= 8,828) of people with dementia in Northern Ireland lived alone. People with dementia who lived alone were younger (mean= 75 years, SD= 8.50) compared to people who lived with a caregiver (mean= 77 years, SD= 7.82). Binary logistic regression highlighted that people who lived alone were more likely to be treated with donepezil medication for dementia and less likely to receive antidepressants. These findings indicate that living alone did not affect treatment for dementia and comorbidity medication in people on dementia medication.

摘要

在英国,大约有三分之一的痴呆症患者独自生活。与与照顾者生活在一起的痴呆症患者相比,独自生活的痴呆症患者可能接受不同的痴呆症治疗,并且可能有不同的合并症。本研究探讨了北爱尔兰独居痴呆症患者与与照顾者生活在一起的痴呆症患者在药物治疗和人口统计学特征方面的差异。通过 2010 年至 2016 年期间首次开处痴呆症管理药物的日期确定痴呆症患者。总共有 25418 人被开处了痴呆症管理药物。关于是否独居的痴呆症患者的数据是通过国家卫生应用和基础设施服务以及通过诚实经纪人服务从国家数据库中提取的。北爱尔兰约有 35%(n=8828)的痴呆症患者独居。与与照顾者生活在一起的痴呆症患者(平均年龄=77 岁,标准差=7.82)相比,独居的痴呆症患者年龄更小(平均年龄=75 岁,标准差=8.50)。二元逻辑回归强调,独居的人更有可能接受痴呆症药物多奈哌齐治疗,而不太可能接受抗抑郁药治疗。这些发现表明,独居并未影响痴呆症药物治疗和合并症药物治疗。

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本文引用的文献

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Factors Associated with Mortality Including Nursing Home Transitions: A Retrospective Analysis of 25,418 People Prescribed Anti-Dementia Drugs in Northern Ireland.与死亡率相关的因素,包括入住养老院:对北爱尔兰 25418 名开抗痴呆症药物处方的人的回顾性分析。
J Alzheimers Dis. 2020;73(3):1233-1242. doi: 10.3233/JAD-190751.
2
Living Alone with Alzheimer's Disease: Data from SveDem, the Swedish Dementia Registry.独居阿尔茨海默病患者:来自瑞典痴呆症登记处 SveDem 的数据。
J Alzheimers Dis. 2017;58(4):1265-1272. doi: 10.3233/JAD-170102.
3
Trends in the Prescription and Long-Term Utilization of Antidementia Drugs Among Patients with Alzheimer's Disease in Spain: A Cohort Study Using the Registry of Dementias of Girona.西班牙阿尔茨海默病患者抗痴呆药物的处方和长期使用趋势:一项基于赫罗纳痴呆症登记处的队列研究
Drugs Aging. 2017 Apr;34(4):303-310. doi: 10.1007/s40266-017-0446-x.
4
Potentially Inappropriate Prescribing Among People with Dementia in Primary Care: A Retrospective Cross-Sectional Study Using the Enhanced Prescribing Database.基层医疗中痴呆患者潜在不适当处方情况:一项使用强化处方数据库的回顾性横断面研究
J Alzheimers Dis. 2016 Apr 11;52(4):1503-13. doi: 10.3233/JAD-151177.
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Living Alone with Dementia: Prevalence, Correlates and the Utilization of Health and Nursing Care Services.独居痴呆症患者:患病率、相关因素及健康与护理服务利用情况
J Alzheimers Dis. 2016;52(2):619-29. doi: 10.3233/JAD-151058.
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Living Alone with Alzheimer's Disease and the Risk of Adverse Outcomes: Results from the Plan de Soin et d'Aide dans la maladie d'Alzheimer Study.独居与阿尔茨海默病及不良后果风险:来自阿尔茨海默病护理与援助计划研究的结果
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