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99mTc-HYNIC-[D-Phe1, Tyr3-Octreotide] SPECT/CT 对成人髓母细胞瘤的显像研究。

Adult Medulloblastoma Depicted With 99mTc-HYNIC-[D-Phe1, Tyr3-Octreotide] SPECT/CT.

机构信息

From the Department of Nuclear Medicine, University Hospital of Patras, Rion Patras, Greece.

出版信息

Clin Nucl Med. 2020 Dec;45(12):1001-1002. doi: 10.1097/RLU.0000000000003341.

Abstract

Although medulloblastoma constitutes the second most common malignant brain tumor in children, it encountered very rarely in adults. The incidence of adult medulloblastoma is approximately 0.6 to 1 case per million. It accounts for less than 1% of adult brain tumors and is located most commonly at the posterior cranial fossa. We present an extremely rare case of a 67-year-old man with cerebellar medulloblastoma with residual disease after surgery, chemotherapy, and radiation therapy, depicted with Tc-HYNIC-[D-Phe, Tyr-Octreotide] SPECT/CT. Somatostatin receptor scintigraphy was performed for staging and for the possibility of treatment with somatostatin analogs or peptide radionuclide therapy.

摘要

尽管髓母细胞瘤构成了儿童中第二常见的恶性脑肿瘤,但在成人中非常罕见。成人髓母细胞瘤的发病率约为每百万人口 0.6 至 1 例。它占成人脑肿瘤的比例不到 1%,最常见于颅后窝。我们报告了一例非常罕见的病例,一名 67 岁男性患有小脑髓母细胞瘤,手术后、化疗和放疗后仍有残留疾病,Tc-HYNIC-[D-Phe,Tyr-Octreotide]SPECT/CT 显示。进行生长抑素受体闪烁显像以进行分期,并考虑使用生长抑素类似物或肽放射性核素治疗。

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