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地舒单抗停药后 6 个月内显著的骨密度损失:一例报告。

Remarkable loss of bone mineral density in 6 months after denosumab discontinuation: a case report.

机构信息

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

Center of Osteoporosis and Spinal Disorders, Kamimura Orthopedic Clinic, Matsumoto, Japan.

出版信息

Mod Rheumatol Case Rep. 2020 Jul;4(2):218-221. doi: 10.1080/24725625.2019.1702494. Epub 2020 Jan 6.

Abstract

In recent years, several studies have shown that multiple vertebral fractures sometimes occur after denosumab discontinuation. Herein, we report the case of a 63-year-old woman with osteoporosis who lost 60% of lumbar bone mineral density acquired during osteoporosis treatment after 6 months of denosumab discontinuation.

摘要

近年来,有几项研究表明,在停止使用地舒单抗后有时会发生多处椎体骨折。在此,我们报告了一例骨质疏松症患者,一名 63 岁女性,在停止地舒单抗治疗 6 个月后,其获得的腰椎骨密度丢失了 60%。

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