Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Center of Osteoporosis and Spinal Disorders, Kamimura Orthopedic Clinic, Matsumoto, Japan.
Mod Rheumatol Case Rep. 2020 Jul;4(2):218-221. doi: 10.1080/24725625.2019.1702494. Epub 2020 Jan 6.
In recent years, several studies have shown that multiple vertebral fractures sometimes occur after denosumab discontinuation. Herein, we report the case of a 63-year-old woman with osteoporosis who lost 60% of lumbar bone mineral density acquired during osteoporosis treatment after 6 months of denosumab discontinuation.
近年来,有几项研究表明,在停止使用地舒单抗后有时会发生多处椎体骨折。在此,我们报告了一例骨质疏松症患者,一名 63 岁女性,在停止地舒单抗治疗 6 个月后,其获得的腰椎骨密度丢失了 60%。