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来自巴迪亚波泽韦里修道院墓地(意大利卢卡)的一例13世纪囊性棘球蚴病。

A 13th-century cystic echinococcosis from the cemetery of the monastery of Badia Pozzeveri (Lucca, Italy).

作者信息

Fornaciari Antonio, Gaeta Raffaele, Cavallini Letizia, Aringhieri Giacomo, Ishak Randa, Bruschi Fabrizio, Giuffra Valentina

机构信息

Division of Paleopathology, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Italy.

Division of Paleopathology, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Italy.

出版信息

Int J Paleopathol. 2020 Dec;31:79-88. doi: 10.1016/j.ijpp.2020.10.005. Epub 2020 Oct 20.

Abstract

OBJECTIVE

To differentially diagnose a calcified formation recovered from a 13th century AD grave from the Tuscan monastery of Badia Pozzeveri, Lucca, Italy.

MATERIALS

A calcified formation from the thoraco-abdominal region of a skeleton buried in the monastery cemetery.

METHODS

Cone Beam Computed Tomography, Scanning Electron Microscope and Energy Dispersive X-Ray Spectroscopy.

RESULTS

A hollow, calcified ovoid formation was identified as typical of a hydatid cyst, permitting the diagnosis of cystic echinococcosis in a 35-45year-old female.

CONCLUSIONS

The study reveals the circulation of the parasite Echinococcus granulosus in the region of Lucca in late medieval Tuscany.

SIGNIFICANCE

This finding is the fourth case of cystic echinococcosis from an archaeological context in Italy and provides insight into environmental conditions that appear to have affected members of a community, irrespective of social status.

LIMITATIONS

Caution and the application of multiple analyses must be exercised in the differential diagnosis to discriminate among calcified formations.

SUGGESTIONS FOR FURTHER RESEARCH

Analysis of stable isotopes of the calcified formation, such as N and C, in order to compare them with isotopic values of the host individual and to further confirm the parasitic origin of the find.

摘要

目的

对从意大利卢卡巴迪亚波泽韦里托斯卡纳修道院一座公元13世纪坟墓中出土的钙化结构进行鉴别诊断。

材料

取自该修道院墓地一具骨架胸腹区域的钙化结构。

方法

锥形束计算机断层扫描、扫描电子显微镜和能量色散X射线光谱分析。

结果

一个中空的钙化卵形结构被鉴定为典型的包虫囊肿,由此诊断出一名35 - 45岁女性患有囊型棘球蚴病。

结论

该研究揭示了中世纪晚期托斯卡纳卢卡地区细粒棘球绦虫寄生虫的传播情况。

意义

这一发现是意大利考古背景下囊型棘球蚴病的第四例病例,为了解似乎影响了一个社区成员(无论社会地位如何)的环境状况提供了线索。

局限性

在鉴别诊断钙化结构时必须谨慎并采用多种分析方法。

进一步研究建议

分析钙化结构的稳定同位素,如氮和碳,以便将它们与宿主个体的同位素值进行比较,并进一步确认该发现的寄生虫来源。

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