Sil Shiladitya
Department of Dentistry, Burdwan Medical College and Hospital, Khosbagan, Purba Burdwan, West Bengal, India.
J Family Med Prim Care. 2020 Jul 30;9(7):3733-3736. doi: 10.4103/jfmpc.jfmpc_507_20. eCollection 2020 Jul.
Oral lichen planus (OLP) and oral lichenoid lesions (OLL) have an annual malignant transformation rate of 0.5-2.1%. Lichenoid dysplasia (LD) appears clinically similar to OLP, OLL but histologically harbors atypical cells for which it has a greater potential for malignant transformation. The case reports of two female patients are reported here, which were clinically diagnosed as OLP, later as LD following histopathological confirmation. Both had positive tobacco history and extensive intra-oral lesions. Habit cessation was supplemented by non-steroidal therapeutics with periodic follow-up. There was reduction in the burning sensation, lesion size, and the degree of inflammation of the lesions. Clinical lichenoid like features warrants a biopsy to rule out OLP, OLL from LD. Except for palliation, lesion oriented proper therapeutic treatment should be instituted only after histopathological confirmation.
口腔扁平苔藓(OLP)和口腔苔藓样病变(OLL)的年恶变率为0.5 - 2.1%。苔藓样发育异常(LD)在临床上与OLP、OLL相似,但在组织学上含有非典型细胞,因此其恶变潜力更大。本文报告了两名女性患者的病例,她们临床上最初被诊断为OLP,经组织病理学确诊后为LD。两人都有吸烟史且口腔内病变广泛。除了戒烟外,还采用非甾体类疗法并定期随访。烧灼感、病变大小及病变炎症程度均有所减轻。临床出现苔藓样特征时,需进行活检以排除OLP、OLL与LD。除了缓解症状外,只有在组织病理学确诊后才应进行针对病变的适当治疗。