Lee Rebecca A, Dassios Theodore, Bhat Ravindra, Greenough Anne
Neonatal Intensive Care Centre, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.
Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Science and Medicine, King's College London, London SE5 9RS, UK.
Case Rep Pediatr. 2020 Oct 13;2020:8824556. doi: 10.1155/2020/8824556. eCollection 2020.
Bilious vomiting in the newborn is common and requires urgent attention to exclude malrotation. The proportion of neonates with surgical abnormalities, however, is small, and there are other causes. . We reviewed our experience of infants with bilious vomiting to demonstrate the importance of input from the tertiary surgical and medical team to arrive at the correct diagnosis.
Admissions with bilious vomiting/aspirates of term born infants over a three-year period to a tertiary medical and surgical unit were reviewed.
During the study period, 48 infants were admitted with bilious vomiting. Forty-five infants had upper gastrointestinal (UGI) contrast studies, and only six had an abnormal study: four had malrotation and two had Hirschsprung's disease. Of the infants with a normal UGI study, no cause was identified in 20 cases, 13 infants were treated for sepsis, one had a meconium plug, one an ovarian cyst, and two infants were polycythaemic. One infant was diagnosed with bilateral polymicrogyria (PMG) on brain MRI and another was found to have hypochondroplasia FGFR3 skeletal dysplasia.
Neonates with bilious vomiting may have a variety of underlying diagnoses and need to be referred to a tertiary surgical and medical centre to ensure appropriate diagnosis is made.
新生儿胆汁性呕吐很常见,需要紧急关注以排除肠旋转不良。然而,患有外科异常的新生儿比例较小,还有其他病因。我们回顾了我们对胆汁性呕吐婴儿的治疗经验,以证明三级外科和医疗团队的意见对于做出正确诊断的重要性。
回顾了在三年期间入住三级医疗和外科单位的足月出生婴儿胆汁性呕吐/吸出物的情况。
在研究期间,48名婴儿因胆汁性呕吐入院。45名婴儿进行了上消化道(UGI)造影检查,只有6名检查结果异常:4名患有肠旋转不良,2名患有先天性巨结肠。在UGI检查正常的婴儿中,20例未发现病因,13名婴儿因败血症接受治疗,1名有胎粪堵塞,1名有卵巢囊肿,2名婴儿患有红细胞增多症。1名婴儿在脑部MRI上被诊断为双侧多小脑回(PMG),另1名被发现患有软骨发育不全FGFR3骨骼发育异常。
胆汁性呕吐的新生儿可能有多种潜在诊断,需要转诊至三级外科和医疗中心以确保做出适当诊断。