Hwong Alison R, Schmittdiel Julie, Schillinger Dean, Newcomer John W, Essock Susan, Zhu Zheng, Dyer Wendy, Young-Wolff Kelly C, Mangurian Christina
University of California, San Francisco, Weill Institute of Neurosciences, Department of Psychiatry, USA.
Kaiser Permanente Northern California Division of Research, Oakland, CA, USA.
Addict Behav. 2021 Mar;114:106697. doi: 10.1016/j.addbeh.2020.106697. Epub 2020 Oct 14.
Smoking is a significant modifiable risk factor for mortality for persons with serious mental illness (SMI), who have a life expectancy 15-20 years shorter than the general population. Individuals with SMI and comorbid diabetes who are smokers face an even higher risk of cardiovascular complications and early death. Yet despite high rates of smoking among people with SMI, tobacco cessation interventions have not been broadly offered to this population.
We conducted a retrospective cohort study using electronic health records from 2014 in a large integrated care delivery system to examine whether use of smoking cessation pharmacotherapy among smokers with type 2 diabetes varies by serious mental illness (SMI) diagnosis. We analyzed smoking cessation medication prescription fills among adult smokers with diabetes, comparing those with SMI (N = 634) and without SMI (N = 18,021). Risk ratios were adjusted for age, gender, race, urban area type, and medical facility.
Of the SMI group, 19.09% filled at least one smoking cessation prescription compared to 9.73% of the non-SMI group (adjusted risk ratio 1.80 [95% CI 1.52-2.13]; p < .001). For the SMI group, primary care providers wrote 80.24% of prescriptions, while psychiatrists wrote 8.81% of prescriptions.
These findings offer an example of a delivery system with higher uptake of smoking cessation pharmacotherapy among people with SMI than without SMI, and highlight the opportunity to provide more smoking cessation interventions in mental health care settings.
吸烟是严重精神疾病(SMI)患者死亡的一个重要可改变风险因素,这类患者的预期寿命比普通人群短15至20年。患有SMI且合并糖尿病的吸烟者面临更高的心血管并发症和过早死亡风险。然而,尽管SMI患者吸烟率很高,但戒烟干预措施尚未广泛提供给这一人群。
我们使用2014年大型综合医疗服务系统中的电子健康记录进行了一项回顾性队列研究,以检查2型糖尿病吸烟者中戒烟药物治疗的使用是否因严重精神疾病(SMI)诊断而异。我们分析了成年糖尿病吸烟者的戒烟药物处方配药情况,比较了患有SMI的患者(N = 634)和未患有SMI的患者(N = 18,021)。风险比率根据年龄、性别、种族、城市地区类型和医疗机构进行了调整。
在SMI组中,19.09%的人至少配了一张戒烟处方,而非SMI组为9.73%(调整后的风险比率为1.80 [95% CI 1.52 - 2.13];p <.001)。对于SMI组,初级保健提供者开出了80.24%的处方,而精神科医生开出了8.81%的处方。
这些发现表明,在一个医疗服务系统中,患有SMI的人群比未患有SMI的人群对戒烟药物治疗的接受度更高,并突出了在精神卫生保健环境中提供更多戒烟干预措施的机会。