无创通气与脊髓损伤。

Noninvasive Ventilation and Spinal Cord Injury.

机构信息

Department of Medicine, John D. Dingell VA Medical Center, Wayne State University, Detroit Medical Center, 3990 John R St, Detroit, MI 48201, USA; Department of Medicine, Wayne State University, Detroit, MI, USA; Detroit Medical Center, Detroit, MI, USA.

Department of Medicine, John D. Dingell VA Medical Center, Wayne State University, Detroit Medical Center, 3990 John R St, Detroit, MI 48201, USA; Department of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Wayne State University, 3990 John R, 3-Hudson, Detroit, MI 48201, USA; Ascension Providence Hospital, Southfield, MI, USA.

出版信息

Sleep Med Clin. 2020 Dec;15(4):461-470. doi: 10.1016/j.jsmc.2020.08.006. Epub 2020 Oct 6.

DOI:10.1016/j.jsmc.2020.08.006

PMID:33131657

Abstract

Individuals with spinal cord injury (SCI) are at increased risk of respiratory complications during wake and sleep. Sleep-disordered breathing (SDB) is commonly associated with SCI and requires an individualized approach to its management. Respiratory control plays a key role in the pathogenesis of SDB in cervical SCI. Noninvasive ventilation plays an important role in the management of respiratory complications in individuals with SCI acutely and in chronic phases. Positive airway pressure treatment may be effective in eliminating SDB and improving sleepiness symptoms, but adherence to treatment is poor and effect on long-term outcomes is questionable.

摘要

脊髓损伤（SCI）患者在清醒和睡眠期间有发生呼吸并发症的风险增加。睡眠呼吸障碍（SDB）通常与 SCI 相关，需要对其管理采取个体化的方法。呼吸控制在颈段 SCI 中 SDB 的发病机制中起着关键作用。在 SCI 急性和慢性阶段，无创通气在管理呼吸并发症方面发挥着重要作用。气道正压治疗可能对消除 SDB 和改善嗜睡症状有效，但治疗的依从性较差，对长期结果的影响也存在疑问。