血清素综合征/血清素中毒
Serotonin Syndrome/Serotonin Toxicity.
作者信息
Talton Cynthia Wright
机构信息
is a Nurse Practitioner in the Outpatient Mental Health Clinic at the Veterans Affairs Medical Center in Salem, Virginia.
出版信息
Fed Pract. 2020 Oct;37(10):452-459. doi: 10.12788/fp.0042.
Abstract
OBJECTIVE
This review of serotonin syndrome or serotonin toxicity covers the years 2014 to 2019, including information on pathophysiology, etiology, and diagnosis, 3 criteria for diagnosing serotonin syndrome, and criteria for neuroleptic malignant syndrome.
IMPORTANCE
The review highlights the potential lethal combinations of commonly prescribed medications used to treat both veteran and nonveteran patients and includes the latest information on offending medications.
CONCLUSIONS
Prevention of serotonin toxicity includes informed clinicians, patient education, careful prescribing and monitoring, and avoidance of multidrug regimens.
摘要
目的
本关于血清素综合征或血清素中毒的综述涵盖2014年至2019年，包括病理生理学、病因学和诊断方面的信息、血清素综合征的3项诊断标准以及抗精神病药恶性综合征的标准。
重要性
该综述强调了用于治疗退伍军人和非退伍军人患者的常用处方药的潜在致死组合，并包括有关致病药物的最新信息。
结论
预防血清素中毒包括知识渊博的临床医生、患者教育、谨慎开药和监测以及避免多药联用方案。
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