Lee Dae Hyun, Kumar Abhishek, Radoianu Nicoleta, Ehren Lindsey, Bassil Claude
Cardiovascular Medicine, University of South Florida (USF) Health Morsani College of Medicine, Tampa, USA.
Nephrology, University of South Florida (USF) Health Morsani College of Medicine, Tampa, USA.
Cureus. 2020 Sep 28;12(9):e10694. doi: 10.7759/cureus.10694.
Diffuse and nodular glomerulosclerosis is associated with diabetic nephropathy and occasionally with tobacco users. However, it has also been linked with amyloidosis, cryoglobulinemia, and light-chain deposition disease. To the best of our knowledge, there is no published data on diffuse and nodular glomerulosclerosis without light chain deposition in Waldenstrom's macroglobulinemia (WM). We present a case of diffuse and nodular glomerulosclerosis in a non-diabetic, non-smoker with WM.
弥漫性和结节性肾小球硬化与糖尿病肾病相关，偶尔也与吸烟者有关。然而，它也与淀粉样变性、冷球蛋白血症和轻链沉积病有关。据我们所知，尚无关于华氏巨球蛋白血症（WM）中无轻链沉积的弥漫性和结节性肾小球硬化的公开数据。我们报告一例非糖尿病、不吸烟的WM患者发生弥漫性和结节性肾小球硬化的病例。
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