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穿透性角膜移植术后巩膜镜矫正屈光不正和高阶像差的有效性和安全性

Efficiency and Safety of Scleral Lenses in Rehabilitation of Refractive Errors and High Order Aberrations After Penetrating Keratoplasty.

作者信息

Penbe Aysegul, Kanar Hatice Selen, Simsek Saban

机构信息

Department of Ophthalmology, Health Science University, Kartal Dr. Lutfi Kirdar Training and Research Hospital.

出版信息

Eye Contact Lens. 2021 May 1;47(5):301-307. doi: 10.1097/ICL.0000000000000755.

Abstract

OBJECTIVES

Visual rehabilitation after penetrating keratoplasty (PK) has difficulties linked to the high spherical and/or cylindric refractive errors with high order aberrations (HOAs) based on the ocular surface irregularities. We aimed to present the scleral contact lens (SCL)-induced complications and improvements in refractive errors and HOA with SCL fitting in post-PK patients.

METHODS

In this prospective study, 38 eyes of 35 patients who underwent PK and using SCLs were included. Uncorrected visual acuity, best-corrected visual acuity (BCVA), spherical equivalence, manifest astigmatism (Cyl), keratometry, and wavefront analyses of HOAs with corneal topography of all patients were measured before SCL and after 8 hrs of SCL wearing-on. The endothelial cellular density (ECD) changes at 6 months were also recorded. Any complications related to SCL were noted.

RESULTS

All patients showed an improvement in visual acuity with SCL. Uncorrected visual acuity before SCL fitting was 1.15±0.26 log of minimal angle of resolution (logMAR) and BCVA was 0.84±0.24 logMAR. The contact lens-corrected visual acuity decreased to 0.13±0.09 logMAR. Spherical equivalence, Cyl, and keratometry parameters decreased significantly with SCL. The anterior corneal HOAs, coma, and astigmatism coefficients decreased significantly. Conjunctival prolapse (in one eye) and graft rejection episode (in two eyes) were observed during follow-up time (14.25±1.3 months) and they restarted to use SCLs after treatment. The ECD decrease was similar with those who not using SCLs after PK in the literature.

CONCLUSION

Our results indicate that scleral lenses may be a safe and effective option for the treatment of corneal astigmatism and HOAs associated with PK.

摘要

目的

穿透性角膜移植术(PK)后的视力康复存在困难,这与基于眼表不规则性的高球镜和/或柱镜屈光不正以及高阶像差(HOA)有关。我们旨在介绍巩膜接触镜(SCL)引起的并发症,以及PK术后患者佩戴SCL后屈光不正和HOA的改善情况。

方法

在这项前瞻性研究中,纳入了35例行PK并使用SCL的患者的38只眼。在佩戴SCL前及佩戴8小时后,测量所有患者的裸眼视力、最佳矫正视力(BCVA)、等效球镜度、明显散光(柱镜)、角膜曲率测量以及通过角膜地形图进行的HOA波前分析。还记录了6个月时的内皮细胞密度(ECD)变化。记录与SCL相关的任何并发症。

结果

所有患者佩戴SCL后视力均有改善。佩戴SCL前裸眼视力为1.15±0.26最小分辨角对数(logMAR),BCVA为0.84±0.24 logMAR。接触镜矫正视力降至0.13±0.09 logMAR。等效球镜度、柱镜和角膜曲率测量参数在佩戴SCL后显著降低。角膜前表面HOA、彗差和散光系数显著降低。在随访期间(14.25±1.3个月)观察到结膜脱垂(1只眼)和移植排斥反应(2只眼),治疗后他们重新开始佩戴SCL。ECD下降与文献中PK后未使用SCL的患者相似。

结论

我们的结果表明,巩膜镜可能是治疗与PK相关的角膜散光和HOA的一种安全有效的选择。

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