Liu Bowei, Wu Yanfang, Yin Jie, Xiao Jingjing, Si Dongyue, Lin Xue, Ding Haiyan
Center for Biomedical Imaging Research (CBIR), Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, P.R.China.
Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, P.R.China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2020 Oct 25;37(5):892-896. doi: 10.7507/1001-5515.202005003.
Coronary microcirculation dysfunction (CMVD) is an important risk factor for the prognosis of re-perfused ischemic heart. Recent studies showed that the evaluation of CMVD has significant impact on both the early diagnosis of heart diseases relevant to blood supply and prognosis after myocardial reperfusion. In this review, the definition of CMVD from the perspective of pathophysiology was clarified, the principles and features of the state-of-the-art imaging technologies for CMVD assessment were reviewed from the perspective of engineering and the further research direction was promoted.
冠状动脉微循环功能障碍(CMVD)是再灌注缺血性心脏病预后的重要危险因素。近期研究表明,CMVD的评估对与血液供应相关的心脏病早期诊断及心肌再灌注后的预后均有显著影响。本文综述从病理生理学角度阐明了CMVD的定义,从工程学角度回顾了CMVD评估的先进成像技术的原理和特点,并提出了进一步的研究方向。