Department of Radiology, Nagoya City University, Graduate School of Medical Sciences, Nagoya, Japan.
Minim Invasive Ther Allied Technol. 2022 Mar;31(3):389-395. doi: 10.1080/13645706.2020.1830801. Epub 2020 Oct 14.
The aim of this study was to evaluate the usefulness of transcatheter arterial embolization (TAE) using the triaxial system with N-butyl-2-cyanoacrylate (NBCA) for acute arterial bleeding in comparison to TAE using the triaxial system with gelatin sponges (GS) and/or coils.
Between October 2013 and November 2018, 95 patients with acute arterial bleeding underwent emergency TAE using the triaxial system. Six patients underwent multiple TAEs and thus, 104 TAEs using the triaxial system were performed. In 26 of the 104 cases, TAE were performed with NBCA (NBCA group), and in the remaining 78 cases, TAE were performed with GS and/or coils (control group).
Hemorrhagic shock and coagulopathy more often occurred in the NBCA group. Procedure time was shorter in the NBCA group. The technical success rate was 100% in both groups ( > 0.99). The clinical success rate in the NBCA and control groups was 92% and 96%, respectively ( = 0.6). There was one minor complication (4%, 1/26) of liver dysfunction in a patient of the NBCA group, but no complication in the control group ( = 0.26).
TAE using the triaxial system with NBCA may be useful for acute arterial bleeding, especially in patients with hemorrhagic shock and coagulopathy.
本研究旨在评估使用三轴系统结合 N-丁基-2-氰基丙烯酸酯（NBCA）进行急性动脉出血的经导管动脉栓塞（TAE）的有效性，并与使用三轴系统结合明胶海绵（GS）和/或线圈进行 TAE 的效果进行比较。
2013 年 10 月至 2018 年 11 月，95 例急性动脉出血患者接受了三轴系统的紧急 TAE 治疗。其中 6 例患者接受了多次 TAE，因此共进行了 104 例三轴系统的 TAE。在 104 例 TAE 中，26 例采用 NBCA（NBCA 组），其余 78 例采用 GS 和/或线圈（对照组）。
NBCA 组患者更常出现失血性休克和凝血功能障碍。NBCA 组的手术时间更短。两组的技术成功率均为 100%（>0.99）。NBCA 组和对照组的临床成功率分别为 92%和 96%（=0.6）。NBCA 组有 1 例轻微并发症（4%，1/26）为肝功能异常，而对照组无并发症（=0.26）。
使用三轴系统结合 NBCA 的 TAE 可能对急性动脉出血有效，特别是在伴有失血性休克和凝血功能障碍的患者中。
