ICG 荧光导管系统在 TaTME 中避免术中尿道损伤的有效性。
Usefulness of an ICG fluorescence catheter system in TaTME for avoiding intraoperative urethral injury.
机构信息
Department of Surgery, The University of Tokushima, 3-18-15 Kuramoto, Tokushima 770-8503, Japan.
出版信息
J Med Invest. 2020;67(3.4):285-288. doi: 10.2152/jmi.67.285.
BACKGROUND
Sometimes intraoperative urethral injury occurs in Transanal total mesorectal excision (TaTME). The aim of this study is to investigate the usefulness of indocyanine green (ICG) fluorescent catheter system for avoiding intraoperative urethral injury in TaTME in experimental model.
METHODS
A urethral catheter was filled with the mixture of albumin and ICG and raw hams were applied in layers as the surrogate model of rectourethral muscle. The detectability of ICG fluorescence in this catheter was investigated by using laparoscope-type fluorescence camera system.
RESULTS
Fluorescence was detected when ICG was mixed with albumin or peripheral blood. ICG fluorescence could be detected within 4 mm depth of layered raw hams as the surrogate model. Quantitative analysis of the picture detected that ICG fluorescence plateaued in lower concentration than that of serum.
CONCLUSION
ICG fluorescent catheter system may be useful for avoiding intraoperative urethral injury in TaTME. J. Med. Invest. 67 : 285-288, August, 2020.
背景
经肛门全直肠系膜切除术（TaTME）中有时会发生术中尿道损伤。本研究旨在探讨吲哚菁绿（ICG）荧光导尿管系统在 TaTME 中避免术中尿道损伤的实用性，该研究使用实验模型进行。
方法
将尿道导管充满白蛋白和 ICG 的混合物，并用生火腿分层作为直肠尿道肌的替代模型。使用腹腔镜荧光摄像系统研究该导管中 ICG 荧光的检测能力。
结果
当 ICG 与白蛋白或外周血混合时，可检测到荧光。在作为替代模型的分层生火腿中，可检测到 4mm 深处的 ICG 荧光。对检测到的图像进行定量分析表明，ICG 荧光的浓度低于血清时达到平台期。
结论
ICG 荧光导尿管系统可能有助于避免 TaTME 中的术中尿道损伤。医学研究杂志 67:285-288，2020 年 8 月。
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