Rozen Todd D, Robles Hector A
Department of Neurology and Neuroradiology, Mayo Clinic Florida, Jacksonville, USA.
Case Rep Neurol Med. 2020 Oct 23;2020:8849645. doi: 10.1155/2020/8849645. eCollection 2020.
A case is presented of a woman with a history of daily persistent head pressure and dizziness who developed a cytotoxic lesion of the splenium of the corpus callosum after an acute withdrawal of chronic acetazolamide treatment and then, in quick succession, a CSF pressure/volume drop with a lumbar puncture. This is the first documentation that rapid alterations of CSF pressure/volume may trigger cytotoxic lesions in the central nervous system.