Komatsu Hiroshi, Ono Takashi, Maita Yoshinori, Ishida Yusuke, Kikuchi Tatsuo, Maki Takahiro, Hase Satoshi, Sakurai Hisakazu, Oba Akiko, Teshirogi Osamu, Suzuki Akira, Mori Yasuko, Shoji Chikako, Fujita Akira, Takahashi Sachiko, Ebina Takayuki, Ozaki Shinya, Honma Ryuta, Tomita Hiroaki, Kakuto Yoshihisa
Department of Psychiatry, Tohoku University Hospital, Sendai, Miyagi, Japan.
Department of Psychiatry, Miyagi Psychiatric Center, Natori, Miyagi, Japan.
Neuropsychiatr Dis Treat. 2020 Oct 29;16:2553-2561. doi: 10.2147/NDT.S280485. eCollection 2020.
Self-stigma negatively influences self-esteem, quality of life, self-efficacy, treatment adherence, and recovery in psychiatric patients. By revealing personality traits that influence self-stigma, we can gain useful knowledge for the management of self-stigma. A previous meta-analysis indicated that patients with schizophrenia have higher scores on the Autism-Spectrum Quotient (AQ) than healthy controls. However, the relationship between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders remains unclear. Therefore, the present study aimed to reveal the association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders.
We recruited 127 patients with schizophrenia spectrum disorders (schizophrenia, schizoaffective disorder, and delusional disorder). We assessed participants' self-stigma and autistic symptoms using the Internalized Stigma for Mental Illness (ISMI) scale and the Autism-Spectrum Quotient (AQ), respectively. The differences in the scores of ISMI and AQ according to patient characteristics were investigated. Multiple regression analysis controlling for age and gender was performed to determine the relationship between the total scores on the AQ and IMSI scale.
Female patients showed a higher level of self-stigma than males. Unmarried patients showed a significantly higher score on the AQ than married patients. Multiple regression analysis adjusted for age and gender indicated that the total score on AQ might be a predictor of the overall rating on ISMI in patients with schizophrenia spectrum disorders.
This study is the first to reveal the association between autistic symptoms and self-stigma in patients with schizophrenia spectrum disorders. Our results highlight the importance of considering autistic symptoms in the assessment and management of self-stigma in patients with schizophrenia spectrum disorders.
自我污名对精神疾病患者的自尊、生活质量、自我效能感、治疗依从性及康复产生负面影响。通过揭示影响自我污名的人格特质，我们可为自我污名的管理获取有用知识。先前的一项荟萃分析表明，精神分裂症患者在自闭症谱系商数（AQ）上的得分高于健康对照。然而，精神分裂症谱系障碍患者的自闭症症状与自我污名之间的关系仍不明确。因此，本研究旨在揭示精神分裂症谱系障碍患者的自闭症症状与自我污名之间的关联。
我们招募了127例精神分裂症谱系障碍患者（精神分裂症、分裂情感性障碍和妄想性障碍）。我们分别使用内化精神疾病污名量表（ISMI）和自闭症谱系商数（AQ）评估参与者的自我污名和自闭症症状。研究了根据患者特征ISMI和AQ得分的差异。进行了控制年龄和性别的多元回归分析，以确定AQ总分与IMSI量表总分之间的关系。
女性患者的自我污名水平高于男性。未婚患者在AQ上的得分显著高于已婚患者。经年龄和性别调整的多元回归分析表明，AQ总分可能是精神分裂症谱系障碍患者ISMI总体评分的一个预测指标。
本研究首次揭示了精神分裂症谱系障碍患者的自闭症症状与自我污名之间的关联。我们的结果凸显了在精神分裂症谱系障碍患者自我污名的评估和管理中考虑自闭症症状的重要性。
