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小于三个月新生儿和婴儿的心脏导管介入治疗

Cardiac Catheterisation Interventions in Neonates and Infants Less Than Three Months.

作者信息

Alakhfash Ali A, Jelly Ali, Almesned Abdulrahman, Alqwaiee Abdullah, Almutairi Mansour, Salah Sherif, Hasan Mahmoud, Almuhaya Mustafa, Alnajjar Abdulhamid, Mofeed Mohammed, Nasser Bana

机构信息

Prince Sultan Cardiac Centre, Qassim, Saudi Arabia.

Madina Cardiac Centre, Saudi Arabia.

出版信息

J Saudi Heart Assoc. 2020 May 12;32(2):149-156. doi: 10.37616/2212-5043.1051. eCollection 2020.

Abstract

INTRODUCTION

Pediatric cardiac catheterization interventions become an established way of care for selected patients with congenital heart diseases. Cardiac catheterization for neonates and small infants can be challenging. The indications for diagnostic cardiac catheterization have decreased with the advent of advanced non-invasive imaging modalities.

PATIENTS AND METHOD

Between June 2012 and July 2017 patients less than three months who had cardiac catheterization in two centers were reviewed.

RESULTS

During the study period, 174 patients underwent interventional cardiac catheterization,83.3% of them had CHD with two-ventricle circulation and 29 patients (16.7%) had single ventricle pathophysiology. Procedures include diagnostic cath, BAS, balloon pulmonary and aortic valvuloplasty, coarctation angioplasty, and stenting procedures. The vascular access depends upon the type of procedure. All except one had general anesthesia. ICU admission was required on 106 patients (62%). Patients were divided according to the type of cardiac lesion (single versus biventricular pathology) as well as according to the type of intervention (stenting and non-stenting procedures). Comparing these groups revealed that: stent procedures and procedures for patients with single ventricle pathologies were performed at an earlier age, with more contrast, fluoro and procedure time than for non-stent procedures and procedures for patients with biventricular pathologies. Complications include transient arrhythmias in most patients, perforation of the RVOT in one and lower limb hypoperfusion in 12 patients. ICU complications include low cardiac output symptoms (LCOS) in 10 (7%), and sepsis in 8. No intra-procedure mortality. The overall survival was 94%. Ten patients died, with one early and 9 late mortality. 60% of the dead patients had PDA stenting. Reintervention varies according to the patient's diagnosis.

CONCLUSION

Cardiac catheterization intervention an important modality in the management of neonates and infants with critical CHD. Well planned procedures and team expertise are essential. Stenting procedures and procedures for patients with single ventricles carries higher morbidity and mortality.

摘要

引言

小儿心脏导管介入治疗已成为特定先天性心脏病患者既定的治疗方式。对新生儿和小婴儿进行心脏导管插入术可能具有挑战性。随着先进的非侵入性成像方式的出现,诊断性心脏导管插入术的适应症有所减少。

患者与方法

回顾了2012年6月至2017年7月期间在两个中心接受心脏导管插入术的三个月以下患者。

结果

在研究期间,174例患者接受了介入性心脏导管插入术,其中83.3%患有双心室循环的先天性心脏病,29例患者(16.7%)具有单心室病理生理情况。手术包括诊断性导管插入术、体肺分流术、球囊肺动脉和主动脉瓣成形术、缩窄血管成形术和支架置入术。血管通路取决于手术类型。除1例患者外均采用全身麻醉。106例患者(62%)需要入住重症监护病房(ICU)。患者根据心脏病变类型(单心室与双心室病变)以及干预类型(支架置入术和非支架置入术)进行分组。比较这些组发现:与非支架置入术和双心室病变患者的手术相比,支架置入术和单心室病变患者的手术在更早的年龄进行,使用的造影剂更多、透视时间更长且手术时间更长。并发症包括大多数患者出现短暂性心律失常,1例患者出现右心室流出道穿孔,12例患者出现下肢灌注不足。ICU并发症包括10例患者(7%)出现低心排血量症状(LCOS),8例患者出现败血症。术中无死亡病例。总体生存率为94%。10例患者死亡,1例早期死亡,9例晚期死亡。60%的死亡患者接受了动脉导管未闭支架置入术。再次干预根据患者诊断而异。

结论

心脏导管介入治疗是治疗患有严重先天性心脏病的新生儿和婴儿的重要方式。精心规划的手术和团队专业知识至关重要。支架置入术和单心室患者的手术具有更高的发病率和死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6db6/7640550/5c4ec1d42c51/sha-32-02-149f1.jpg

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