The Leicester Royal Infirmary, University Hospitals of Leicester, Leicester, UK.
J Plast Surg Hand Surg. 2021 Apr;55(2):83-95. doi: 10.1080/2000656X.2020.1838295. Epub 2020 Nov 6.
The accurate diagnosis of ulnar collateral ligament (UCL) injuries of the thumb is important in identifying patients requiring surgery. Stener lesion, the most severe form of such injuries, is debilitating and leads to chronic instability if misdiagnosed. We evaluated the diagnostic accuracy of ultrasonography (USS) in UCL injuries. A systematic review of existing literature was performed with a meta-analysis using a bivariate mixed-effects model to estimate summary sensitivity and specificity. All observational studies were assessed, with participants of any age, who sustained UCL injuries of the thumb. A hierarchical model was used to generate a hierarchical summary receiver operating characteristic (HSROC) curves. We identified 17 studies reporting a total of 593 UCL injuries. Pooled estimates for sensitivity and specificity were 0.96 (95% CI 0.89-0.99) and 0.90 (95% CI 0.81-0.94), respectively for the diagnosis of Stener lesions; 0.81 (95% CI 0.66-0.93) and 0.87 (95% CI 0.67-0.96), respectively for non-displaced complete ruptures and 0.82 (95% CI 0.66-0.92) and 0.94 (95% CI 0.85-0.98), respectively for complete ruptures without Stener lesion. The area under the curve (AUC) for Stener diagnosis using USS was 0.98, suggesting excellent diagnostic accuracy. Our meta-analysis suggests that USS is a reliable and accurate method of diagnosis for UCL injuries. Moreover, it has excellent diagnostic accuracy for Stener lesions and may be used in the diagnostic work-up of UCL injuries with magnetic resonance imaging being reserved for ambiguous cases.
准确诊断拇指尺侧副韧带 (UCL) 损伤对于确定需要手术的患者非常重要。Stener 病变是此类损伤中最严重的一种,如果误诊,会导致慢性不稳定。我们评估了超声 (USS) 在 UCL 损伤中的诊断准确性。进行了系统的文献回顾,并进行了荟萃分析,使用双变量混合效应模型来估计汇总敏感性和特异性。评估了所有观察性研究,参与者的年龄不限,均患有拇指 UCL 损伤。使用层次模型生成层次综合受试者工作特征 (HSROC) 曲线。我们确定了 17 项报告总共 593 例 UCL 损伤的研究。汇总估计的敏感性和特异性分别为 0.96(95%CI 0.89-0.99)和 0.90(95%CI 0.81-0.94),用于诊断 Stener 病变;分别为 0.81(95%CI 0.66-0.93)和 0.87(95%CI 0.67-0.96),用于诊断无移位完全断裂;分别为 0.82(95%CI 0.66-0.92)和 0.94(95%CI 0.85-0.98),用于诊断无 Stener 病变的完全断裂。使用 USS 进行 Stener 诊断的曲线下面积 (AUC) 为 0.98,表明诊断准确性很高。我们的荟萃分析表明,USS 是一种可靠且准确的 UCL 损伤诊断方法。此外,它对 Stener 病变具有出色的诊断准确性,并且可以与磁共振成像一起用于 UCL 损伤的诊断,而将 MRI 保留用于模糊病例。