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自体肌腱移植治疗慢性肾病患者的锁骨远端骨折不愈合

Autologous tendon graft for non-union distal clavicle fracture in a patient with chronic kidney disease.

作者信息

Prasetia Renaldi, Aditya Rio, Utoyo Ghuna Arioharjo, Rasyid Hermawan Nagar

机构信息

Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Padjadjaran, Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.

Department of Orthopaedics and Traumatology, Faculty of Medicine, Universitas Padjadjaran, Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.

出版信息

Int J Surg Case Rep. 2020;77:116-121. doi: 10.1016/j.ijscr.2020.10.106. Epub 2020 Oct 28.

Abstract

BACKGROUND

Fracture of distal-end accounts for 20% of all clavicle fracture. In the situation of impaired bone healing environment such as chronic kidney disease (CKD), nonunion rates after surgery might increase. In the case where bone healing is unexpected, biological healing with tendon graft could be an alternative method to maintain bone reduction.

PRESENTATION OF CASE

A 62-year old male with a history of end-stage CKD presented to the hospital with pain, wound, and deformity on the right shoulder. The patient have had surgery in the past 4 months and resulted in a non-union fracture of the distal third right clavicle. The patient underwent implant removal and continued with coracoclavicular ligament reconstruction with autologous tendon grafts of semitendinosus tendon and mini-plate augmentation.

DISCUSSION

The Distal clavicle has a high rate of delayed and nonunion even without the presence of comorbidity. A compromised bone quality frequently leads to failed osteosynthesis in patients with end-stage renal failure. In the advanced stages of kidney disease, problems with a renal clearance of phosphate and low 1ɑ-hydroxylase levels resulting in increased serum phosphate levels and low serum calcium levels. Given these circumstances, we considered the idea to maintain fracture reduction by biologic soft tissue healing of the graft to replace the coracoclavicular ligaments as we can not rely on normal bone strength and healing capacity.

CONCLUSION

In the situation where bone healing is unexpected, biological healing with tendon graft may be necessary. The use of autologous tendon graft and mini-plate suture augmentation could help to maintain bone reduction in such environment.

摘要

背景

锁骨远端骨折占所有锁骨骨折的20%。在诸如慢性肾脏病(CKD)等骨愈合环境受损的情况下,手术后骨不连发生率可能会增加。在骨愈合不理想的情况下,采用肌腱移植进行生物愈合可能是维持骨折复位的一种替代方法。

病例介绍

一名62岁男性,有终末期CKD病史,因右肩部疼痛、伤口及畸形入院。该患者在过去4个月内接受过手术,导致右锁骨远端三分之一处骨折不愈合。患者接受了内固定取出术,并继续采用半腱肌腱自体肌腱移植及微型钢板增强进行喙锁韧带重建。

讨论

即使没有合并症,锁骨远端骨折的延迟愈合和不愈合发生率也很高。骨质量受损常常导致终末期肾衰竭患者骨合成失败。在肾脏疾病晚期,磷酸盐肾清除率问题以及1α-羟化酶水平降低导致血清磷酸盐水平升高和血清钙水平降低。鉴于这些情况,由于我们无法依赖正常的骨强度和愈合能力,我们考虑通过移植的生物软组织愈合来维持骨折复位,以替代喙锁韧带。

结论

在骨愈合不理想的情况下,采用肌腱移植进行生物愈合可能是必要的。在这种情况下,使用自体肌腱移植和微型钢板缝合增强有助于维持骨折复位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd6d/7649590/fb13acd4f5bf/gr1.jpg

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