2019/20年冬季香港儿童流感疫苗接种对预防流感住院的有效性
Influenza vaccination effectiveness in preventing influenza hospitalization in children, Hong Kong, winter 2019/20.
作者信息
Chiu Susan S, Chua Huiying, Kwan Mike Y W, Chan Eunice L Y, Wong Joshua S C, Peiris J S Malik, Cowling Benjamin J
机构信息
Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital and Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region.
WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region.
出版信息
Vaccine. 2020 Dec 3;38(51):8078-8081. doi: 10.1016/j.vaccine.2020.10.081. Epub 2020 Nov 6.
The winter influenza season 2019/20 in Hong Kong was predominated by influenza A(H1N1)pdm09. We analysed an on-going test-negative design study consisting of 1227 children admitted for febrile acute respiratory illness from 3 November 2019 (week 45) to 21 March 2020 (week 12). We estimated influenza vaccine effectiveness of 65% (95% CI: 46 - 78) against hospitalization due to influenza A and B combined, and 74% (95% CI: 54 - 85) against hospitalization due to influenza A(H1N1)pdm09.
2019/20年香港冬季流感季节以甲型（H1N1）pdm09流感为主。我们分析了一项正在进行的检测呈阴性设计研究，该研究纳入了2019年11月3日（第45周）至2020年3月21日（第12周）因发热性急性呼吸道疾病入院的1227名儿童。我们估计，流感疫苗对甲型和乙型流感合并导致的住院的有效性为65%（95%置信区间：46 - 78），对甲型（H1N1）pdm09流感导致的住院的有效性为74%（95%置信区间：54 - 85）。
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