小 RNA 在病毒-宿主相互作用中发挥重要作用。
Small RNA Plays Important Roles in Virus-Host Interactions.
机构信息
Department of Molecular, Cell and Systems Biology, University of California, Riverside 900 University Avenue, Riverside, CA 92521, USA.
出版信息
Viruses. 2020 Nov 7;12(11):1271. doi: 10.3390/v12111271.
Non-coding small RNAs play important roles in virus-host interactions. For hosts, small RNAs can serve as sensors in antiviral pathways including RNAi and CRISPR; for viruses, small RNAs can be involved in viral transcription and replication. This paper covers several recent discoveries on small RNA mediated virus-host interactions, and focuses on influenza virus cap-snatching and a few important virus sensors including PIR-1, RIG-I like protein DRH-1 and piRNAs. The paper also discusses recent advances in mammalian antiviral RNAi.
非编码小 RNA 在病毒-宿主相互作用中发挥着重要作用。对于宿主来说，小 RNA 可以作为抗病毒途径（包括 RNAi 和 CRISPR）中的传感器；对于病毒来说，小 RNA 可以参与病毒的转录和复制。本文涵盖了小 RNA 介导的病毒-宿主相互作用的几个最新发现，并重点介绍了流感病毒的帽结合窃取以及一些重要的病毒传感器，包括 PIR-1、RIG-I 样蛋白 DRH-1 和 piRNA。本文还讨论了哺乳动物抗病毒 RNAi 的最新进展。
Zotero 插件