Department of Cardiothoracic and Vascular surgery, Aarhus University Hospital, Aarhus, Denmark.
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Scand Cardiovasc J. 2021 Apr;55(2):116-121. doi: 10.1080/14017431.2020.1846775. Epub 2020 Nov 11.
Surgical ablation is an established treatment for patients with atrial fibrillation undergoing cardiac surgery. This study aimed to compare postoperative rhythm outcomes and pacemaker implantation rates after biatrial ablation or pulmonary vein isolation (PVI) concomitantly with other cardiac surgery. In a retrospective study, we included patients who underwent biatrial ablation or PVI. Postoperative rhythm status was assessed by Holter monitoring. All data on outcomes and patient characteristics were collected retrospectively. In total 109 patients had a biatrial procedure whereas 337 had PVI performed. In patients with persistent/long-standing persistent atrial fibrillation, freedom from atrial fibrillation was more common after biatrial ablation than after PVI (63% and 45%, respectively; = .039). Postoperative permanent pacemaker implantation was more common after biatrial ablation (12% and 6%, respectively; = .039), compared to PVI. Age < 65 years (OR:2.0, 95% CI:1.1-3.6) was a predictor of freedom from atrial fibrillation in the biatrial group, whereas absence of left atrial dilatation (OR:1.8, 95% CI:1.1-3.2) and HAS-BLED score < 2 (OR:1.9, 95% CI:1.0-3.8) were significant predictors of freedom from atrial fibrillation in the PVI group. In patients with persistent/long-standing persistent atrial fibrillation, biatrial ablation is more effective than PVI in terms of obtaining freedom from postoperative atrial fibrillation. Although our groups were heterogenic in terms of concomitant surgery, our study also indicates that the risk of needing a permanent pacemaker is higher after biatrial ablation, compared to PVI. Therefore, our study highlights that the decision between biatrial ablation or PVI should be performed on an individual basis.
心房颤动患者行心脏手术时,外科消融术是一种既定的治疗方法。本研究旨在比较同期行双侧心房消融或肺静脉隔离(PVI)与其他心脏手术时的术后节律结果和起搏器植入率。 在一项回顾性研究中,我们纳入了行双侧心房消融或 PVI 的患者。通过动态心电图监测评估术后节律状态。所有关于结局和患者特征的数据均回顾性收集。 共有 109 例患者行双侧心房消融术,337 例患者行 PVI。持续性/持久性心房颤动患者中,双侧心房消融术后房颤无复发率高于 PVI(分别为 63%和 45%; = .039)。双侧心房消融术后永久性起搏器植入更常见(分别为 12%和 6%; = .039),与 PVI 相比。年龄 < 65 岁(OR:2.0,95%CI:1.1-3.6)是双侧心房消融组无房颤的预测因素,而左心房不扩张(OR:1.8,95%CI:1.1-3.2)和 HAS-BLED 评分 < 2(OR:1.9,95%CI:1.0-3.8)是 PVI 组无房颤的显著预测因素。 在持续性/持久性心房颤动患者中,双侧心房消融术在获得术后无房颤方面比 PVI 更有效。尽管我们的两组患者在同期手术方面存在异质性,但我们的研究还表明,与 PVI 相比,双侧心房消融术后需要永久性起搏器的风险更高。因此,我们的研究强调,双侧心房消融或 PVI 的选择应根据个体情况进行。