NeuroAllergy Research Laboratory (NARL), School of Life and Environmental Sciences, Faculty of Science, Engineering and Built Environment, Deakin University, Waurn Ponds, VIC, Australia; NeuroAllergy Research Laboratory (NARL), School of Life and Environmental Sciences, Faculty of Science, Engineering and Built Environment, Deakin University, Burwood, VIC, Australia; Deakin AIRwatch Pollen and Spore Counting and Forecasting Facility, Deakin University, Burwood and Waurn Ponds, VIC, Australia.
NeuroAllergy Research Laboratory (NARL), School of Life and Environmental Sciences, Faculty of Science, Engineering and Built Environment, Deakin University, Burwood, VIC, Australia; Deakin AIRwatch Pollen and Spore Counting and Forecasting Facility, Deakin University, Burwood and Waurn Ponds, VIC, Australia.
J Allergy Clin Immunol Pract. 2021 Apr;9(4):1510-1515. doi: 10.1016/j.jaip.2020.10.022. Epub 2020 Oct 22.
Epidemic thunderstorm asthma (ETSA) is a global health problem that can strike without sufficient warning and can have catastrophic consequences. Because of climate change, future events are likely to become more common, more disastrous, and more unpredictable. To prevent loss of life and avoid surge events on health care infrastructure, identifying at-risk individuals and their potential biomarkers is the most prophylactic approach that can be taken to mitigate the deadly consequences of ETSA. In this review, we provide an update on the clinical mechanism, global prevalence, and characteristics of those patients moderately or severely at risk of ETSA. Identifying these patient characteristics will aid clinical professionals to provide suitable and personalized treatment plans and, in turn, avoid future loss of life.
暴发性雷暴哮喘(ETSA)是一个全球性的健康问题,可能在没有充分预警的情况下突然发作,并可能带来灾难性的后果。由于气候变化,未来的事件可能会更加普遍、更具灾难性且更难预测。为了防止生命损失和避免医疗基础设施的激增事件,识别高危个体及其潜在的生物标志物是可以采取的最具预防性的方法,可以减轻 ETSA 的致命后果。在这篇综述中,我们提供了暴发性雷暴哮喘的临床机制、全球流行情况以及那些处于中高度风险的患者特征的最新信息。识别这些患者特征将有助于临床专业人员提供合适和个性化的治疗计划,从而避免未来的生命损失。