The management of uremia.

Progressive uremia is the hallmark of many renal diseases, some reversible. The signs and symptoms tend to parallel the declining glomerular filtration rate. With an understanding of the usual progression, the physician is equipped to plan therapy. Hypertension must be treated. Phosphorus binding, protein limitation and fluid and electrolyte control can be started at appropriate times and managed fairly easily. There are several cycles of deterioration that can be reversed if recognized promptly.