Division of General Surgery, Department of Surgery, Morsani College of Medicine, the University of South Florida, Tampa, Florida.
Ann Surg. 2022 Aug 1;276(2):293-297. doi: 10.1097/SLA.0000000000004421. Epub 2020 Nov 17.
To assess 4 measures of the accumulating deficits model of frailty for postoperative mortality and readmissions including their stability over time.
Frailty has been assessed by multiple methods. It is unclear whether variation in how frailty is measured is important and would be stable over time.
Rockwood's 57-item frailty index was mapped onto 14,568 ICD9 diagnosis codes from Healthcare Cost and Utilization Project State Inpatient Database for the state of Florida (HCUP-SID-FL) for calendar years 2011 to 2015, inclusive, with 962 ICD9 codes matching onto 42 items. This became the modified frailty index (mFI) used. Three measures of the mFI were differentiated: the number of admission diagnoses, number of chronic conditions upon admission, and number of increased deficits accumulated during the admission. The Charlson Co-Morbidity Index was a fourth measure of frailty. The mFI of patients who survived or died and were readmitted or not were compared.
Across all years, 4,796,006 patient observations were compared to the number of diagnoses matched on the 42 items of the mFI. The median mFI scores for each method was statistically significantly higher for patients who died compared those that survived and for patients readmitted compared to patients not readmitted for all years. There was little-to-no variation in the year to year median mFI scores.
The 4 methods of calculating frailty performed similarly and were stable. The actual method of determining the accumulated deficits may not be as important as enumerating their number.
评估 4 种衰弱累积模型指标用于术后死亡率和再入院的情况,包括其随时间的稳定性。
衰弱已通过多种方法进行评估。目前尚不清楚测量衰弱的方法的变化是否重要,以及是否会随时间稳定。
将 Rockwood 的 57 项衰弱指数映射到 Healthcare Cost and Utilization Project State Inpatient Database for the state of Florida (HCUP-SID-FL) 中 2011 年至 2015 年的 14568 项 ICD9 诊断代码中,其中 962 项 ICD9 代码匹配到 42 项,成为修改后的衰弱指数(mFI)。将 mFI 分为三个指标:入院诊断数量、入院时的慢性疾病数量和住院期间累积的增加缺陷数量。Charlson 共病指数是第四个衰弱指标。比较了存活或死亡、再入院或未再入院患者的 mFI。
在所有年份中,将 4796006 次患者观察结果与 mFI 的 42 项匹配的诊断数量进行了比较。对于所有年份,死亡患者的 mFI 中位数评分明显高于存活患者,再入院患者的 mFI 中位数评分明显高于未再入院患者。mFI 中位数评分在各年之间的变化很小。
4 种计算衰弱的方法表现相似且稳定。确定累积缺陷的实际方法可能不如计算其数量重要。