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巴西卡西亚斯杜苏尔的炎症性肠病的流行病学特征:一项横断面研究。

Epidemiological profile of inflammatory bowel disease in Caxias do Sul, Brazil: a cross-sectional study.

机构信息

MD. Resident, Department of Internal Medicine, Hospital Geral de Caxias do Sul, Caxias do Sul (RS), Brazil; Resident, Department of Gastroenterology, Hospital de Clínicas de Porto Alegre, Porto Alegre (RS), Brazil.

MD. Physician, School of Medicine, Universidade de Caxias do Sul (UCS), Caxias do Sul (RS), Brazil; Resident, Department of Internal Medicine, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre (RS), Brazil.

出版信息

Sao Paulo Med J. 2020 Nov-Dec;138(6):530-536. doi: 10.1590/1516-3180.2020.0179.R2.10092020.

Abstract

BACKGROUND

Inflammatory bowel diseases affect mostly young patients and have a huge impact on their quality of life and growing treatment costs. Currently, there are few Brazilian studies concerning their epidemiological profile.

OBJECTIVE

The aim of this study was to describe the regional clinical and epidemiological profile of these pathological conditions in Caxias do Sul, Brazil.

DESIGN AND SETTING

Cross-sectional study in Caxias do Sul (RS), Brazil.

METHODS

A search for patients was conducted in the municipality's special medications pharmacy using the International Classification of Diseases, and medical records were manually reviewed for data collection. Sixty-seven patients were included.

RESULTS

The patients' mean age was 46.5 years and females predominated (71.6%). Ulcerative colitis was the most prevalent disease (70%) and Montreal E3 was the most prevalent presentation. The mean age at diagnosis was 39 years. Most patients had recently undergone colonoscopy (67%). Only five patients (7.4%) had records of hospital admission due to the disease, while 12 (18%) underwent a surgical procedure during follow-up. Sixty patients (89.5%) were using aminosalicylates, while less than one fifth were using immunosuppressants or immunobiological drugs: 19.4% and 14.9%, respectively.

CONCLUSION

The profile of inflammatory bowel disease patients in this region of Brazil is similar in some characteristics to other published Brazilian data, although it differs in others such as higher frequency of pancolitis. A prospective study on these patients is planned in this region, in order to improve the data quality.

摘要

背景

炎症性肠病主要影响年轻患者,对其生活质量和不断增加的治疗费用产生巨大影响。目前,巴西针对此类疾病的流行病学特征研究较少。

目的

本研究旨在描述巴西卡西亚斯杜苏尔地区此类病理状况的区域临床和流行病学特征。

设计与设置

巴西卡西亚斯杜苏尔的横断面研究。

方法

在该市的特殊药物药房使用国际疾病分类搜索患者,并对医疗记录进行手动审查以收集数据。共纳入 67 例患者。

结果

患者的平均年龄为 46.5 岁,女性居多(71.6%)。溃疡性结肠炎是最常见的疾病(70%),且以蒙特利尔 E3 型最常见。诊断时的平均年龄为 39 岁。大多数患者最近接受过结肠镜检查(67%)。仅有 5 例(7.4%)患者因该疾病住院记录,12 例(18%)在随访期间接受了手术。60 例(89.5%)患者使用了氨基水杨酸盐,而不到五分之一的患者使用了免疫抑制剂或免疫生物药物:分别为 19.4%和 14.9%。

结论

巴西该地区炎症性肠病患者的特征在某些方面与其他已发表的巴西数据相似,但在其他方面存在差异,如全结肠炎的发病率更高。计划在该地区对这些患者进行前瞻性研究,以提高数据质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f38/9685572/b1445e56f1b4/1806-9460-spmj-138-06-530-gf01.jpg

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