Grau-Roma Llorenç, Navarro Mauricio, Blatter Sohvi, Wenker Christian, Kittl Sonja, Uzal Francisco A, Posthaus Horst
Institute of Animal Pathology, Vetsuisse Faculty, 27210University of Bern, Bern, Switzerland.
California Animal Health and Food Safety Laboratory System, 8789University of California, Davis, San Bernardino, CA, USA.
Vet Pathol. 2021 Mar;58(2):423-427. doi: 10.1177/0300985820971788. Epub 2020 Nov 19.
Several outbreaks of necrotic enteritis-like disease in lorikeets, from which was consistently isolated, are described. All lorikeets had acute, segmental, or multifocal fibrinonecrotizing inflammatory lesions in the small and/or the large intestine, with intralesional gram-positive rods. The gene encoding alpha toxin was detected by PCR (polymerase chain reaction) on formalin-fixed, paraffin-embedded (FFPE) tissues in 20 out of 24 affected lorikeets (83%), but it was not amplified from samples of any of 10 control lorikeets ( < .0001). The second most prevalent toxin gene detected was the beta toxin gene, which was found in FFPE from 7 out of 24 affected lorikeets (29%). The other toxin genes were detected inconsistently and in a relatively low number of samples. These cases seem to be associated with , although the specific type involved could not be determined.
本文描述了几起吸蜜鹦鹉坏死性肠炎样疾病的爆发,从中持续分离出[具体病原体未给出]。所有吸蜜鹦鹉在小肠和/或大肠均有急性、节段性或多灶性纤维蛋白坏死性炎症病变,病变内可见革兰氏阳性杆菌。通过聚合酶链反应(PCR)在24只受影响吸蜜鹦鹉中的20只(83%)的福尔马林固定、石蜡包埋(FFPE)组织中检测到编码α毒素的基因,但在10只对照吸蜜鹦鹉的任何样本中均未扩增到该基因(P<0.0001)。检测到的第二常见毒素基因是β毒素基因,在24只受影响吸蜜鹦鹉中的7只(29%)的FFPE样本中发现。其他毒素基因检测结果不一致,且样本数量相对较少。这些病例似乎与[具体病原体未给出]有关,尽管无法确定所涉及的具体类型。