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板层角膜移植术治疗晚期圆锥角膜。

Lamellar Keratoplasty for Advanced Keratoconus.

机构信息

Singapore National Eye Centre, Singapore.

Singapore Eye Research Institute, Singapore.

出版信息

Asia Pac J Ophthalmol (Phila). 2020 Dec;9(6):580-588. doi: 10.1097/APO.0000000000000338.

Abstract

Ectatic corneal diseases are a group of disorders resulting in progressive corneal steepening and thinning. Keratoconus, keratoglobus, pellucid marginal degeneration, post-keratorefractive ectasia, and corneal graft ectasia are the types of corneal ectasia. Early diagnosis with appropriate diagnostic tools can help prevent progression, eliminating the need for corneal transplantation. Lamellar or full thickness corneal transplantation are the treatment options for advanced diseases. Although the visual outcomes of penetrating keratoplasty are comparable to anterior lamellar keratoplasty (ALK) especially in keratoconus, ALK is the preferred treatment of choice considering benefits including reduced graft rejection, less long-term complications, and better graft survival. This article reviews the various surgical techniques in ALK with its clinical outcomes in advanced keratoconus.

摘要

扩张性角膜疾病是一组导致进行性角膜变陡和变薄的疾病。圆锥角膜、球形角膜、边缘性角膜营养不良、屈光性角膜后扩张和角膜移植后扩张是角膜扩张的类型。早期使用适当的诊断工具进行诊断有助于防止疾病进展,从而避免角膜移植的需要。板层或全层角膜移植是晚期疾病的治疗选择。尽管穿透性角膜移植的视力结果与前板层角膜移植(ALK)相当,尤其是在圆锥角膜中,但考虑到减少移植物排斥、较少的长期并发症和更好的移植物存活率等益处,ALK 是首选的治疗方法。本文综述了 ALK 的各种手术技术及其在晚期圆锥角膜中的临床效果。

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