Université de Paris, Paris, France; GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte-Anne, CMME, Paris, France.
Université de Paris, Paris, France; GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte-Anne, CMME, Paris, France; McGill Group for suicide studies, McGill University, Montréal, Canada; Nîmes academic hospital (CHU), Nîmes, France; Equipe Moods, INSERM UMR-1178, Paris, France.
J Affect Disord. 2021 Feb 1;280(Pt A):241-249. doi: 10.1016/j.jad.2020.11.052. Epub 2020 Nov 12.
Studies showed disadvantageous decision-making in suicide attempters. The present meta-analysis aims to examine the stability of these findings and related questions.
EMBASE and Pubmed databases were searched for studies published between 01/01/2000 and 01/01/2020 with an additional search through bibliographical references. English or French articles published in peer-reviewed journals, reporting quantitative task-based measures of decision-making in suicide attempters were included: 3,582 records were identified, 33 full-text articles screened, and 21 articles finally included.
All studies were conducted in mood disorders; 18 used the Iowa Gambling Task (IGT) and 3 the Cambridge Gamble Task (CGT). With the IGT, suicide attempters showed riskier choices than patient controls (Hedges' g=-0.28 95%CI (-0.44 - -0.12)) and healthy controls (g=-0.54 (-0.83 - -0.25)) with no significant difference between control groups. The difference between suicide attempters and patient controls was not related to age group, mood disorder type, author, or research center while an effect of time of publication was found (p=0.006). Poorer performance was also found in suicide attempters compared to patient controls when using the CGT (g=-0.57 95%CI (-0.82 - -0.31)). Suicide attempters who used a violent means showed poorer IGT performance than those who used a non-violent means (3 studies).
Limited number of studies outside mood disorders. No data to calculate a gender effect.
The present meta-analysis confirmed riskier decision-making in suicide attempters. Although group differences appear to be of modest effect size in general, they were particularly marked in the subgroup of those who used a violent suicidal means.
研究表明,自杀未遂者在决策方面存在不利之处。本荟萃分析旨在检验这些发现的稳定性及相关问题。
检索了 EMBASE 和 Pubmed 数据库,纳入了 2000 年 1 月 1 日至 2020 年 1 月 1 日期间发表的研究,同时通过参考文献进行了额外搜索。纳入了发表在同行评议期刊上的英语或法语文章,报告了自杀未遂者基于任务的决策定量测量结果:共识别出 3582 条记录,筛选了 33 篇全文文章,最终纳入了 21 篇文章。
所有研究均在心境障碍患者中进行;18 项研究使用了 Iowa 赌博任务(IGT),3 项研究使用了剑桥赌博任务(CGT)。在使用 IGT 时,自杀未遂者的风险选择行为比患者对照组(Hedges' g=-0.28,95%CI:-0.44 至-0.12)和健康对照组(g=-0.54,-0.83 至-0.25)更差,而对照组之间无显著差异。自杀未遂者与患者对照组之间的差异与年龄组、心境障碍类型、作者或研究中心无关,但发现了发表时间的影响(p=0.006)。与患者对照组相比,自杀未遂者在使用 CGT 时的表现也更差(g=-0.57,95%CI:-0.82 至-0.31)。使用暴力手段自杀的自杀未遂者的 IGT 表现比使用非暴力手段自杀的自杀未遂者更差(3 项研究)。
心境障碍以外的研究数量有限。没有数据可计算性别效应。
本荟萃分析证实了自杀未遂者存在风险决策。尽管总体而言,组间差异的效应大小似乎较小,但在使用暴力自杀手段的亚组中,差异尤其显著。