Department of Cardiovascular Medicine, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
Cardiol Clin. 2021 Feb;39(1):119-142. doi: 10.1016/j.ccl.2020.09.008.
Peripartum cardiomyopathy (PPCM) is a form of heart failure that occurs toward the end of pregnancy or in the months following pregnancy and is marked by left ventricular systolic dysfunction. The cause of PPCM remains unknown and there is no diagnostic test specific to PPCM. Outcomes vary and include complete left ventricular recovery, persistent cardiac dysfunction, transplant, and death. Numerous advances have been made in understanding this disease, but many knowledge gaps remain. This article reviews recent data and recommendations for clinical practice in addition to highlighting the multiple knowledge gaps related to PPCM that warrant further investigation.
围生期心肌病（PPCM）是一种心力衰竭的形式，发生在妊娠末期或产后数月，以左心室收缩功能障碍为特征。PPCM 的病因仍然未知，也没有针对 PPCM 的特定诊断测试。结局各不相同，包括完全左心室恢复、持续的心功能障碍、移植和死亡。人们对这种疾病的认识有了很大的进步，但仍有许多知识空白。本文综述了最近的数据和临床实践建议，同时强调了与 PPCM 相关的多个需要进一步研究的知识空白。
