Tiengo Cesare, Sonda Regina, Messana Francesco, Masciopinto Giuseppe, Trovarelli Giulia, Berizzi Antonio, Ruggeri Pietro, Bassetto Franco
Clinic of Plastic Reconstructive and Aesthetic Surgery, Padova University Hospital, Padova, Italy.
Department of Orthopedics and Orthopedic Oncology, Padova University Hospital, Padova, Italy.
SAGE Open Med Case Rep. 2020 Nov 5;8:2050313X20970021. doi: 10.1177/2050313X20970021. eCollection 2020.
Tumor seeding after intra-abdominal and head and neck cancer surgery is a well-known entity. The risk of disseminating cancerous cells during surgery is also described for soft-tissue sarcoma of the extremities. Nonetheless, after reconstructive surgery using flaps, the risk of recurrence at the donor site is extremely rare. Up to this date, the literature describes only three cases, but none of them reported a translocated recurrence after a reconstruction with a propeller flap. Here, we report a case of high-grade pleomorphic sarcoma of the knee, which recurred at the proximal edge of a propeller flap 28 months after the first excision surgery. The reasons for such local recurrences are not clear and previous works have advocated different theories: direct contamination by tumor cells, physical manipulation of the tumor and creation of surgical wounds with tumor supportive properties. Although these particular cases of recurrence are exceedingly rare, certain precautionary meticulous surgical techniques and a thorough preoperative planning are pivotal to avoid the contamination of "clean" areas during the first excision surgery.
腹内及头颈癌手术后的肿瘤种植是一个广为人知的现象。肢体软组织肉瘤手术过程中播散癌细胞的风险也有相关描述。尽管如此,使用皮瓣进行重建手术后,供区复发的风险极其罕见。截至目前,文献仅报道了3例,但均未提及螺旋桨皮瓣重建后出现移位复发的情况。在此,我们报告1例膝部高级别多形性肉瘤病例,该病例在首次切除手术后28个月于螺旋桨皮瓣近端边缘复发。这种局部复发的原因尚不清楚,既往研究提出了不同的理论:肿瘤细胞直接污染、肿瘤的物理操作以及形成具有肿瘤支持特性的手术创面。尽管这些特殊的复发病例极为罕见,但某些预防性的精细手术技术和全面的术前规划对于避免首次切除手术期间“清洁”区域的污染至关重要。