血管内成像技术对易损斑块的成像：优势与局限
imaging of vulnerable plaque with intravascular modalities: its advantages and limitations.
作者信息
Kitahara Satoshi, Kataoka Yu, Sugane Hiroki, Otsuka Fumiyuki, Asaumi Yasuhide, Noguchi Teruo, Yasuda Satoshi
机构信息
Department of Cardiovascular Medicine, National Cerebral & Cardiovascular Center, Suita, Osaka, Japan.
Department of Cardiovascular Medicine, Chikamori Hospital, Kochi, Japan.
出版信息
Cardiovasc Diagn Ther. 2020 Oct;10(5):1461-1479. doi: 10.21037/cdt-20-238.
Abstract
imaging of plaque instability has been considered to have a great potential to predict future coronary events and evaluate the stabilization effect of novel anti-atherosclerotic medical therapies. Currently, there are several intravascular imaging modalities which enable to visualize plaque components associated with its vulnerability. These include virtual histology intravascular ultrasound (VH-IVUS), integrated backscatter IVUS (IB-IVUS), optical coherence tomography (OCT), near-infrared spectroscopy and coronary angioscopy. Recent studies have shown that these tools are applicable for risk stratification of cardiovascular events as well as drug efficacy assessment. However, several limitation exists in each modality. The current review paper will outline advantages and limitation of VH-IVUS, IB-IVUS, OCT, NIRS and coronary angioscopy imaging.
摘要
斑块不稳定性成像被认为在预测未来冠状动脉事件以及评估新型抗动脉粥样硬化药物治疗的稳定效果方面具有巨大潜力。目前，有几种血管内成像方式能够使与斑块易损性相关的斑块成分可视化。这些方式包括虚拟组织学血管内超声（VH-IVUS）、背向散射积分血管内超声（IB-IVUS）、光学相干断层扫描（OCT）、近红外光谱以及冠状动脉血管镜检查。最近的研究表明，这些工具适用于心血管事件的风险分层以及药物疗效评估。然而，每种方式都存在一些局限性。本综述文章将概述VH-IVUS、IB-IVUS、OCT、近红外光谱（NIRS）和冠状动脉血管镜检查成像的优点和局限性。
相似文献
1
imaging of vulnerable plaque with intravascular modalities: its advantages and limitations.
Cardiovasc Diagn Ther. 2020 Oct;10(5):1461-1479. doi: 10.21037/cdt-20-238.
2
Intracoronary imaging modalities for vulnerable plaques.
J Nippon Med Sch. 2011;78(6):340-51. doi: 10.1272/jnms.78.340.
3
The Role of Intracoronary Plaque Imaging with Intravascular Ultrasound, Optical Coherence Tomography, and Near-Infrared Spectroscopy in Patients with Coronary Artery Disease.
Curr Atheroscler Rep. 2016 Sep;18(9):57. doi: 10.1007/s11883-016-0607-0.
4
Additive Value of Integrated Backscatter IVUS for Detection of Vulnerable Plaque by Optical Frequency Domain Imaging: An Ex Vivo Autopsy Study of Human Coronary Arteries.
JACC Cardiovasc Imaging. 2016 Feb;9(2):163-72. doi: 10.1016/j.jcmg.2015.07.011. Epub 2016 Jan 6.
5
Intracoronary Imaging of Vulnerable Plaque-From Clinical Research to Everyday Practice.
J Clin Med. 2022 Nov 9;11(22):6639. doi: 10.3390/jcm11226639.
6
Advances in Intravascular Imaging: New Insights into the Vulnerable Plaque from Imaging Studies.
Korean Circ J. 2018 Jan;48(1):1-15. doi: 10.4070/kcj.2017.0182. Epub 2017 Nov 9.
7
Multimodality imaging of attenuated plaque using grayscale and virtual histology intravascular ultrasound and optical coherent tomography.
Catheter Cardiovasc Interv. 2016 Jul;88(1):E1-E11. doi: 10.1002/ccd.25786. Epub 2016 May 9.
8
In vivo characterization of coronary plaques: novel findings from comparing greyscale and virtual histology intravascular ultrasound and near-infrared spectroscopy.
Eur Heart J. 2012 Feb;33(3):372-83. doi: 10.1093/eurheartj/ehr387. Epub 2011 Oct 20.
9
Near-Infrared Spectroscopy Intravascular Ultrasound Imaging: State of the Art.
Front Cardiovasc Med. 2020 Jun 30;7:107. doi: 10.3389/fcvm.2020.00107. eCollection 2020.
10
Diagnostic accuracy of optical coherence tomography and integrated backscatter intravascular ultrasound images for tissue characterization of human coronary plaques.
J Am Coll Cardiol. 2006 Jul 4;48(1):81-8. doi: 10.1016/j.jacc.2006.02.062. Epub 2006 Jun 9.
引用本文的文献
1
Intracoronary Optical Coherence Tomography: Technological Innovations and Clinical Implications in Cardiology.
Curr Treat Options Cardiovasc Med. 2025;27(1):44. doi: 10.1007/s11936-025-01103-4. Epub 2025 Jul 24.
2
MicroRNA Inhibiting Atheroprotective Proteins in Patients with Unstable Angina Comparing to Chronic Coronary Syndrome.
Int J Mol Sci. 2024 Oct 2;25(19):10621. doi: 10.3390/ijms251910621.
3
Label-free atherosclerosis diagnosis through a blood drop of apolipoprotein E knockout mouse model using surface-enhanced Raman spectroscopy validated by machine learning algorithm.
Bioeng Transl Med. 2023 May 3;8(4):e10529. doi: 10.1002/btm2.10529. eCollection 2023 Jul.
4
Novel ultrasound techniques in the identification of vulnerable plaques-an updated review of the literature.
Front Cardiovasc Med. 2023 May 24;10:1069745. doi: 10.3389/fcvm.2023.1069745. eCollection 2023.
5
Intracoronary Imaging of Vulnerable Plaque-From Clinical Research to Everyday Practice.
J Clin Med. 2022 Nov 9;11(22):6639. doi: 10.3390/jcm11226639.
6
Non-Coding RNAs in Regulating Plaque Progression and Remodeling of Extracellular Matrix in Atherosclerosis.
Int J Mol Sci. 2022 Nov 8;23(22):13731. doi: 10.3390/ijms232213731.
7
detection of plaque erosion by intravascular optical coherence tomography using artificial intelligence.
Biomed Opt Express. 2022 Jun 16;13(7):3922-3938. doi: 10.1364/BOE.459623. eCollection 2022 Jul 1.
8
Effect of long-term intensive cholesterol control on the plaque progression in elderly based on CTA cohort study.
Eur Radiol. 2022 Jul;32(7):4374-4383. doi: 10.1007/s00330-022-08594-w. Epub 2022 Feb 28.
9
What Is Hidden Behind Yellow Pixels: from Pathology to Intravascular Imaging of Atherosclerotic Plaque.
Curr Atheroscler Rep. 2022 Feb;24(2):97-108. doi: 10.1007/s11883-022-00990-3. Epub 2022 Feb 2.
10
The impact of lipid-lowering medications on coronary artery plaque characteristics.
Am J Prev Cardiol. 2021 Nov 9;8:100294. doi: 10.1016/j.ajpc.2021.100294. eCollection 2021 Dec.
本文引用的文献
1
Cholesterol-crystalized coronary atheroma as a potential precursor lesion causing acute coronary syndrome: a case report.
Eur Heart J Case Rep. 2019 Jul 16;3(3):ytz128. doi: 10.1093/ehjcr/ytz128. eCollection 2019 Sep.
2
Identification of patients and plaques vulnerable to future coronary events with near-infrared spectroscopy intravascular ultrasound imaging: a prospective, cohort study.
Lancet. 2019 Nov 2;394(10209):1629-1637. doi: 10.1016/S0140-6736(19)31794-5. Epub 2019 Sep 27.
3
Relationship between coronary plaque morphology of the left anterior descending artery and 12 months clinical outcome: the CLIMA study.
Eur Heart J. 2020 Jan 14;41(3):383-391. doi: 10.1093/eurheartj/ehz520.
4
Plaque erosion or coronary artery embolism? Findings from clinical presentation, optical coherence tomographic and histopathological analysis in a case with acute coronary syndrome.
Int J Cardiovasc Imaging. 2019 Oct;35(10):1791-1792. doi: 10.1007/s10554-019-01641-6. Epub 2019 Jun 6.
5
Impact of combined plaque structural stress and wall shear stress on coronary plaque progression, regression, and changes in composition.
Eur Heart J. 2019 May 7;40(18):1411-1422. doi: 10.1093/eurheartj/ehz132.
6
Effect of Evolocumab on Coronary Plaque Composition.
J Am Coll Cardiol. 2018 Oct 23;72(17):2012-2021. doi: 10.1016/j.jacc.2018.06.078.
7
A randomized controlled trial of eicosapentaenoic acid in patients with coronary heart disease on statins.
J Cardiol. 2017 Dec;70(6):537-544. doi: 10.1016/j.jjcc.2017.07.007. Epub 2017 Aug 31.
8
Effect of Ezetimibe on Stabilization and Regression of Intracoronary Plaque - The ZIPANGU Study.
Circ J. 2017 Oct 25;81(11):1611-1619. doi: 10.1253/circj.CJ-17-0193. Epub 2017 Jun 8.
9
Near-infrared spectroscopy-derived lipid core burden index predicts adverse cardiovascular outcome in patients with coronary artery disease during long-term follow-up.
Eur Heart J. 2018 Jan 21;39(4):295-302. doi: 10.1093/eurheartj/ehx247.
10
Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography: A 4-Year Follow-Up Study.
J Am Coll Cardiol. 2017 May 23;69(20):2502-2513. doi: 10.1016/j.jacc.2017.03.556.
Zotero 插件