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双侧疱疹性角结膜炎在化脓性汗腺炎背景下的表现:病例报告及文献复习。

Bilateral Phlyctenular Keratoconjunctivitis in the Context of Hidradenitis Suppurativa: A Case Report and Literature Review.

机构信息

Ophthalmology Department, Hospital Obispo Polanco, Teruel, Spain.

Dermatology Department, Hospital Obispo Polanco, Teruel, Spain.

出版信息

Ocul Immunol Inflamm. 2022 May 19;30(4):992-994. doi: 10.1080/09273948.2020.1833223. Epub 2020 Nov 23.

Abstract

PURPOSE

To report a case of severe bilateral phlyctenular keratoconjunctivitis (PKC) associated to hidradenitis suppurativa (HS).

CASE REPORT

A 26-year-old male with reactivation of HS in the last few months presented with concurrent pain and vision loss secondary to bilateral PKC resistant to topical treatment. There were no other infectious or autoimmune disorders. Systemic immunosuppression was needed, with simultaneous improvement of the ophthalmological and dermatological findings.

CONCLUSIONS

Different inflammatory eye diseases have been reported in the context of HS. Acute inflammation in HS reactivation would trigger an autoimmune response, acting as a common causal mechanism in this association. We have reported a new case of inflammatory eye disease - HS in the form of PKC, not previously described in the literature, and consistent with immune dysregulation where the systemic burden due to HS may act as an additional causal factor.

摘要

目的

报告一例严重的双侧疱疹性角结膜炎(PKC)合并化脓性汗腺炎(HS)。

病例报告

一名 26 岁男性,近几个月 HS 复发,出现双侧 PKC,伴有疼痛和视力丧失,局部治疗无效。无其他感染或自身免疫性疾病。需要全身免疫抑制,同时改善眼科和皮肤科的发现。

结论

HS 可引起不同的炎症性眼病。HS 复发的急性炎症会引发自身免疫反应,这可能是两者关联的共同病因机制。我们报告了一例新的炎症性眼病 - HS 表现为 PKC,这在文献中尚未描述,与免疫失调一致,HS 引起的全身负担可能是一个额外的病因因素。

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