Children's Hospital Los Angeles.
Roski Eye Institute, University of Southern California, Los Angeles, California, USA.
Curr Opin Neurol. 2021 Feb 1;34(1):89-96. doi: 10.1097/WCO.0000000000000877.
Cortical visual impairment (CVI) is the leading cause of pediatric visual impairment in developed countries. Currently, there is no standardized method of visual assessment in these children, who usually cannot participate in tests designed for typically developing children. A reproducible method of visual assessment that accurately reflects the multitude of visual deficits in CVI is critical to evaluate proposed therapies for this disorder. This review analyzes current research on methods of visual assessment in children with CVI.
Earlier studies focused on measuring visual acuity in children with CVI. More recent studies have emphasized other aspects of visual function, such as contrast sensitivity, motion detection, and visual search. Current research topics include questionnaires, functional vision assessment (CVI Range), neuropsychological tests of visual perception, and eye tracking. Eye tracking shows promise for visual assessment in both clinical and research settings because it is objective and quantitative, with the ability to assess diverse visual parameters.
Current research on visual assessment in children with CVI focuses on measuring deficits of visual function beyond visual acuity. This research represents an important step toward designing clinical trials to identify effective therapeutics for this increasingly prevalent disorder with heterogeneous manifestations.
皮质视觉障碍(CVI)是发达国家儿童视力障碍的主要原因。目前,这些儿童通常无法参与为正常发育儿童设计的测试,因此没有标准化的视觉评估方法。对于这种疾病,评估所提出的治疗方法的关键是要有一种可重复的视觉评估方法,该方法能够准确反映 CVI 患者的多种视觉缺陷。本文分析了目前针对 CVI 患儿视觉评估方法的研究。
早期研究集中在评估 CVI 患儿的视力。最近的研究强调了视觉功能的其他方面,如对比敏感度、运动检测和视觉搜索。目前的研究课题包括问卷调查、CVI 范围的功能性视觉评估、视觉感知神经心理学测试和眼动追踪。眼动追踪在临床和研究环境中的视觉评估中具有广阔的应用前景,因为它具有客观性和定量性,能够评估多种视觉参数。
目前针对 CVI 患儿视觉评估的研究侧重于测量视力以外的视觉功能缺陷。这项研究对于设计临床试验以确定针对这种表现形式多样的日益流行疾病的有效治疗方法具有重要意义。