Jiang Chao, Wang Ting, Xu Yong-Cheng, Gao Ying, Fang Bang-Jiang
The Third Department of Neurology, The Second Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi.
Department of Emergency, Longhua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai.
Medicine (Baltimore). 2020 Nov 25;99(48):e23187. doi: 10.1097/MD.0000000000023187.
This retrospective study investigated the effect of Yiqi-Huoxue Decoction (YQHXD) on blood pressure (BP) in patients with acute ischemic stroke (AIS).A total of 72 patients with BP following AIS who received routine treatment were included in this retrospective study. Of those, 36 patients received YQHXD and were assigned to a treatment group. The other 36 patients were allocated to a control group. All patients were treated for a total of 4 months. The outcomes were assessed by systolic blood pressure (SBP), diastolic blood pressure (DBP), National Institutes of Health Stroke Scale (NIHSS) score and Barthel index scale (BIS). All outcomes were measured after 4-month treatment.After treatment, all subjects in the treatment group showed greater improvements in SBP (P < .05), DBP (P < .05), NIHSS (P < .05) score, and BIS (P < .05) than those of patients in the control group. In addition, the safety profile is similar in both groups.The findings of this study demonstrated that YQHXD may benefit on BP in patients with AIS. Future studies should focus on warranting the current results.
这项回顾性研究调查了益气活血汤（YQHXD）对急性缺血性脑卒中（AIS）患者血压（BP）的影响。本回顾性研究纳入了72例接受常规治疗的AIS后血压患者。其中，36例患者接受益气活血汤治疗并被分配到治疗组。另外36例患者被分配到对照组。所有患者共治疗4个月。通过收缩压（SBP）、舒张压（DBP）、美国国立卫生研究院卒中量表（NIHSS）评分和巴氏指数量表（BIS）评估结果。所有结果均在治疗4个月后测量。治疗后，治疗组所有受试者的SBP（P<0.05）、DBP（P<0.05）、NIHSS（P<0.05）评分和BIS（P<0.05）均比对照组患者有更大改善。此外，两组的安全性概况相似。本研究结果表明，益气活血汤可能对AIS患者的血压有益。未来的研究应侧重于证实当前结果。
