Delbrück H, Wetter O, Schmidt C G, Weichert C, Linder K H
Dtsch Med Wochenschr. 1977 Sep 9;102(36):1273-9. doi: 10.1055/s-0028-1105492.
75 cases treated between 1970 and 1976 for malignant follicular non-Hodgkin's lymphoma were analysed for their cardinal signs. Contrary to non-Hodgkin's lymphoma of "higher malignancy degree", the average age of patients with malignant follicular non-Hodgkin's lymphoma is generally over 50 years, being more common in females. By the time the diagnosis is made a generalised stage has usually been reached. In the described group of patients the five-year survival rate was 65%, but compared with the malignant lymphoma of higher malignancy the prognosis is often complicated by secondary diseases resulting from the higher age. The findings confirm the need for histological sub-classification of malignant non-Hodgkin's lymphoma.
对1970年至1976年间接受治疗的75例恶性滤泡性非霍奇金淋巴瘤患者的主要体征进行了分析。与“恶性程度较高”的非霍奇金淋巴瘤相反,恶性滤泡性非霍奇金淋巴瘤患者的平均年龄一般超过50岁,女性更为常见。在确诊时通常已处于广泛期。在所描述的患者组中,五年生存率为65%,但与恶性程度较高的恶性淋巴瘤相比,由于年龄较大,预后常因继发疾病而复杂化。这些发现证实了对恶性非霍奇金淋巴瘤进行组织学亚分类的必要性。