Center for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
JACC Cardiovasc Imaging. 2021 Apr;14(4):854-866. doi: 10.1016/j.jcmg.2020.09.027. Epub 2020 Nov 25.
With the advent of transcatheter mitral valve replacement (TMVR), the concept of the neo-left ventricular outflow tract (LVOT) was introduced and remains an essential component of treatment planning. This paper describes the LVOT anatomy and provides a step-by-step computed tomography methodology to segment and measure the neo-LVOT while discussing the current evidence and outstanding challenges. It also discusses the technical and hemodynamic factors that play a major role in assessing the neo-LVOT. A summary of expert-based recommendations about the overall risk of LVOT obstruction in different scenarios is presented along with the currently available methods to reduce the risk of LVOT obstruction and other post-procedural complications.
随着经导管二尖瓣置换术(TMVR)的出现,新左心室流出道(LVOT)的概念被引入,并仍然是治疗计划的重要组成部分。本文描述了 LVOT 的解剖结构,并提供了一种逐步的 CT 方法来分割和测量新的 LVOT,同时讨论了当前的证据和悬而未决的挑战。还讨论了在评估新的 LVOT 中起主要作用的技术和血液动力学因素。本文还总结了关于不同情况下 LVOT 阻塞总体风险的专家建议,以及目前降低 LVOT 阻塞和其他术后并发症风险的可用方法。