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使用改良五项虚弱指数和营养状况预测行腰椎融合术患者的术后并发症。

Predicting postoperative complications in patients undergoing lumbar spinal fusion by using the modified five-item frailty index and nutritional status.

机构信息

Department of Orthopaedics Korea University College of Medicine, Anam Hospital, Seoul, Korea.

出版信息

Bone Joint J. 2020 Dec;102-B(12):1717-1722. doi: 10.1302/0301-620X.102B12.BJJ-2020-0874.R1.

Abstract

AIMS

As the population ages and the surgical complexity of lumbar spinal surgery increases, the preoperative stratification of risk becomes increasingly important. Understanding the risks is an important factor in decision-making and optimizing the preoperative condition of the patient. Our aim was to determine whether the modified five-item frailty index (mFI-5) and nutritional parameters could be used to predict postoperative complications in patients undergoing simple or complex lumbar spinal fusion.

METHODS

We retrospectively reviewed 584 patients who had undergone lumbar spinal fusion for degenerative lumbar spinal disease. The 'simple' group (SG) consisted of patients who had undergone one- or two-level posterior lumbar fusion. The 'complex' group (CG) consisted of patients who had undergone fusion over three or more levels, or combined anterior and posterior surgery. On admission, the mFI-5 was calculated and nutritional parameters collected.

RESULTS

Complications occurred in 9.3% (37/396) of patients in the SG, and 10.1% (19/167) of patients in the CG. In the SG, the important predictors of complications were age (odds ratio (OR) 1.036; p = 0.002); mFI-5 (OR 1.026 to 2.411, as score increased to 1 ≥ 2 respectively p = 0.023); albumin (OR 11.348; p < 0.001); vitamin D (OR 2.185; p = 0.032); and total lymphocyte count (OR 1.433; p = 0.011) . In the CG, the predictors of complications were albumin (OR 9.532; p = 0.002) and vitamin D (OR 3.815; p = 0.022).

CONCLUSION

The mFI-5 and nutritional status were effective predictors of postoperative complications in the SG, but only nutritional status was successful in predicting postoperative complications in the CG. The complexity of the surgery, as well as the preoperative frailty and nutritional status of patients, should be considered when determining if it is safe to proceed with lumbar spinal fusion. Cite this article: 2020;102-B(12):1717-1722.

摘要

目的

随着人口老龄化和腰椎脊柱手术复杂性的增加,术前风险分层变得越来越重要。了解风险是决策和优化患者术前状况的重要因素。我们的目的是确定改良的五项目虚弱指数(mFI-5)和营养参数是否可用于预测接受简单或复杂腰椎脊柱融合的患者的术后并发症。

方法

我们回顾性分析了 584 例因退行性腰椎脊柱疾病接受腰椎脊柱融合的患者。“简单”组(SG)包括接受 1 或 2 个节段后路腰椎融合的患者。“复杂”组(CG)包括接受 3 个或更多节段融合或前后联合手术的患者。入院时,计算 mFI-5 并收集营养参数。

结果

SG 中并发症发生率为 9.3%(37/396),CG 中并发症发生率为 10.1%(19/167)。在 SG 中,并发症的重要预测因素是年龄(优势比(OR)1.036;p = 0.002);mFI-5(OR 1.026 至 2.411,评分分别增加至 1≥2,p = 0.023);白蛋白(OR 11.348;p <0.001);维生素 D(OR 2.185;p = 0.032);和总淋巴细胞计数(OR 1.433;p = 0.011)。在 CG 中,并发症的预测因素是白蛋白(OR 9.532;p = 0.002)和维生素 D(OR 3.815;p = 0.022)。

结论

mFI-5 和营养状况是 SG 术后并发症的有效预测因素,但只有营养状况成功预测了 CG 术后并发症。在决定是否安全进行腰椎脊柱融合时,应考虑手术的复杂性以及患者术前的脆弱性和营养状况。

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