Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Curr Eye Res. 2021 Jul;46(7):954-960. doi: 10.1080/02713683.2020.1857781. Epub 2020 Dec 15.
: To investigate the characteristics of margin reflex distance 1 (MRD1) asymmetry in congenital lower eyelid epiblepharon and its resolution after surgical correction of epiblepharon.: Among patients who underwent lower eyelid epiblepharon surgery from November 2015 to September 2017, patients with a preoperative MRD1 difference of more than 1.0 mm between the two eyes according to medical photographs were defined as having MRD1 asymmetry. A postoperative MRD1 difference of less than 1.0 mm between the two eyes was regarded as MRD1 asymmetry resolution. The preoperative MRD1 difference was compared between subgroups with resolved or sustained MRD1 asymmetry. Astigmatism and amblyopia were also assessed.: Among 432 patients, MRD1 asymmetry was observed in 24 patients (5.6%). MRD1 was always lower in the side with more extensive epiblepharon. At 6 months after surgery, the mean MRD1 difference between the two eyes was significantly decreased (1.8 ± 0.7 mm to 0.5 ± 0.8 mm, < .001, paired t-test) and MRD1 asymmetry resolution occurred in 19 patients (79%). In the resolved MRD1 asymmetry group, the preoperative MRD1 difference was 2.0 mm or less and was significantly smaller than that in the sustained MRD1 asymmetry group ( = .010, Mann-Whitney U test). Six patients had preoperative aniso-astigmatism ≥ 1.50 D. Unilateral amblyopia presented in nine patients (38%) and improved within 1 year postoperatively.: MRD1 asymmetry can be resolved after epiblepharon surgery, especially when the preoperative MRD1 difference is 2.0 mm or less. Unilateral amblyopia was frequent, but the treatment outcome was good.
: 探讨先天性下睑皮赘的边缘反射距离 1（MRD1）不对称的特征及其皮赘矫正术后的缓解情况。：在 2015 年 11 月至 2017 年 9 月期间接受下睑皮赘手术的患者中，根据术前照片，双眼术前 MRD1 差值大于 1.0mm 的患者定义为存在 MRD1 不对称。双眼术后 MRD1 差值小于 1.0mm 则认为是 MRD1 不对称缓解。比较缓解和持续存在 MRD1 不对称的亚组之间的术前 MRD1 差值。还评估了散光和弱视的情况。：在 432 例患者中，24 例（5.6%）观察到 MRD1 不对称。MRD1 总是在皮赘更广泛的一侧更低。术后 6 个月，双眼之间的平均 MRD1 差值显著降低（1.8±0.7mm 至 0.5±0.8mm，<.001，配对 t 检验），19 例（79%）患者缓解了 MRD1 不对称。在缓解的 MRD1 不对称组中，术前 MRD1 差值为 2.0mm 或更小，且明显小于持续存在的 MRD1 不对称组（=0.010，Mann-Whitney U 检验）。6 例患者术前存在≥1.50D 的散光性散光。9 例患者（38%）出现单侧弱视，术后 1 年内得到改善。：皮赘手术后 MRD1 不对称可以缓解，特别是术前 MRD1 差值为 2.0mm 或更小时。单侧弱视比较常见，但治疗效果良好。
