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老年性前庭病、合并症与残疾认知:一项横断面研究

Presbyvestibulopathy, Comorbidities, and Perception of Disability: A Cross-Sectional Study.

作者信息

Soto-Varela Andrés, Rossi-Izquierdo Marcos, Del-Río-Valeiras María, Vaamonde-Sánchez-Andrade Isabel, Faraldo-García Ana, Lirola-Delgado Antonio, Santos-Pérez Sofía

机构信息

Division of Neurotology, Department of Otorhinolaryngology, Complexo Hospitalario Universitario, Santiago de Compostela, Spain.

Department of Surgery and Medical-Surgical Specialities, University of Santiago de Compostela, Santiago de Compostela, Spain.

出版信息

Front Neurol. 2020 Oct 30;11:582038. doi: 10.3389/fneur.2020.582038. eCollection 2020.

Abstract

To assess the perception of disability in patients with presbyvestibulopathy and to determine the factors (demographic, balance test scores, and comorbidities) that determine higher levels of disability. This was a cross-sectional study conducted in a tertiary university hospital. There were 103 patients who fulfilled the diagnostic criteria for presbyvestibulopathy and were included. Dizziness Handicap Inventory (DHI) score was the main variable used to quantify disability. Influence on DHI score, sex, age, time of evolution, equilibriometric parameters (posturographic scores and timed up and go test), history of falls, comorbidities (high blood pressure, diabetes, and dyslipidemia), psychotropic drug use, tobacco or alcohol use, living environment (urban or rural), and active lifestyle were analyzed. Most of the DHI scores showed a moderate (46 patients, 44.7%) or severe (39 participants, 37.9%) handicap. DHI scores were higher in women (59.8 vs. 36.1, < 0.001), patients with obesity (58.92 vs. 48.68; = 0.019), benzodiazepine (59.9 vs. 49.1, = 0.008) or other psychotropic drug (60.7 vs. 49.2, = 0.017) users, and fallers (57.1 vs. 47.3, = 0.048). There was also a significant positive correlation between DHI score, time (Rho coefficient: 0.371, < 0.001), and steps (Rho coefficient: 0.284, = 0.004) used in the TUG and with the short FES-I questionnaire (a shortened version of the Falls Efficacy Scale-International) score (Rho coefficient: 0.695, < 0.001). DHI scores were lower in alcohol consumers than in non-drinkers (46.6 vs. 56, = 0.048). No significant correlation was found between DHI scores and age, time of evolution, posturographic scores, comorbidities, environment (rural or urban), or active lifestyle. Most patients with presbyvestibulopathy show an important subjective perception of disability in relation to their symptoms. This perception is substantially higher in women than in men. The most influential factors are difficulties in walking, fear of falling, and obesity. NCT03034655, www.clinicaltrials.gov.

摘要

评估老年前庭病患者的残疾认知,并确定决定更高残疾水平的因素(人口统计学因素、平衡测试分数和合并症)。这是一项在三级大学医院进行的横断面研究。纳入了103名符合老年前庭病诊断标准的患者。头晕残障量表(DHI)得分是用于量化残疾的主要变量。分析了性别、年龄、病程、平衡测量参数(姿势描记分数和计时起立行走测试)、跌倒史、合并症(高血压、糖尿病和血脂异常)、精神药物使用情况、烟草或酒精使用情况、生活环境(城市或农村)以及积极生活方式对DHI得分的影响。大多数DHI得分显示为中度(46例患者,44.7%)或重度(39名参与者,37.9%)残疾。女性(59.8对36.1,<0.001)、肥胖患者(58.92对48.68;=0.019)、苯二氮䓬类药物使用者(59.9对49.1,=0.008)或其他精神药物使用者(60.7对49.2,=0.017)以及有跌倒史者(57.1对47.3,=0.048)的DHI得分更高。DHI得分与计时起立行走测试中所用时间(Rho系数:0.371,<0.001)、步数(Rho系数:0.284,=0.004)以及简短FES-I问卷(国际跌倒效能量表的简化版)得分(Rho系数:0.695,<0.001)之间也存在显著正相关。饮酒者的DHI得分低于不饮酒者(46.6对56,=0.048)。未发现DHI得分与年龄、病程、姿势描记分数、合并症、环境(农村或城市)或积极生活方式之间存在显著相关性。大多数老年前庭病患者对其症状表现出重要的主观残疾认知。这种认知在女性中明显高于男性。最有影响的因素是行走困难、害怕跌倒和肥胖。NCT03034655,www.clinicaltrials.gov。

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